| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:IONIS-DNM2-2.5Rx(Synonyms:DYM101)
CAS:2857839-05-3
Purity:98% Package:100mg;250mg;1g
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| | IONIS-DNM2-2.5Rx Basic information |
| | IONIS-DNM2-2.5Rx Chemical Properties |
| | IONIS-DNM2-2.5Rx Usage And Synthesis |
| Uses | IONIS-DNM2-2.5Rx (DYM101) is an antisense agent targeting dynamin 2. IONIS-DNM2-2.5Rx has the potential for the research of centronuclear myopathy (CNM)[1]. | | References | [1] Tasfaout H, Buono S, Guo S, et al. Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice. Nat Commun. 2017;8:15661. DOI:10.1038/ncomms15661
[2] Buono S, Ross JA, Tasfaout H, et al. Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy. Proc Natl Acad Sci U S A. 2018;115(43):11066-11071. DOI:10.1073/pnas.1808170115 |
| | IONIS-DNM2-2.5Rx Preparation Products And Raw materials |
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