Pasiniazid manufacturers
- Pasiniazid
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- $50.00 / 1kg
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2022-10-19
- CAS:2066-89-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1
- Pasiniazid USP/EP/BP
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- $1.10 / 1g
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2021-07-17
- CAS:2066-89-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- Pasiniazid
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- $17.00 / 1g
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2021-01-06
- CAS:2066-89-9
- Min. Order: 1g
- Purity: 95%
- Supply Ability: 1KG
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| | Pasiniazid Basic information |
| Product Name: | Pasiniazid | | Synonyms: | isonicotinic acid hydrazide 4-aminosalicylate;ISONICOTINIC ACID HYDRAZIDE P-AMINOSALICYLATE SALT;PASINIAZID;isonicotinicacidhydrazidep-*aminosalicylate;PASINIAZIDISONIAZID AMINOSALICYLATE UV;Dipasic;Fintozid;Nidrapas | | CAS: | 2066-89-9 | | MF: | C13H14N4O4 | | MW: | 290.27 | | EINECS: | 218-183-2 | | Product Categories: | Pharmaceutical Intermediates | | Mol File: | 2066-89-9.mol |  |
| | Pasiniazid Chemical Properties |
| Melting point | 142-144° | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Water |
| | Pasiniazid Usage And Synthesis |
| Originator | Pasinazid, Yick-Vic Chemicals | | Uses | antibacterial (tuberculostatic) | | Uses | Pasiniazid is an antituberculous agents against several species of rapidly growing mycobacteria (RGM). | | Manufacturing Process | 10 parts by weight of isonicotinoyl hydrazine was dissolved in 200 by volume of methanol by stirring at 60°C. Then 11.2 parts 4-aminosalycylic acid was added at 60°C. On cooling a salt of both compounds crystallized as yellow prisms with MP: 135°-140°C (decomposed).
Isonicotinic acid hydrazide compound with 4-aminosalicylic acid may be prepared from the same components by using 750 parts of water by volume as a solvent.
10 parts 4-aminosalicylic acid was dissolved in 600 volume parts of water containing 39 parts by volume 2 N ammonium hydroxide. 9 parts by weight isonicotinoyl hydrazide was added and the mixture was heated to 30°C. The solution was acidified with 49 parts by volume of 2 N acetic acid. On cooling isonicotinic acid hydrazide compound with 4-amino-salicylic acid crystallized, which decomposed at 135°-140°C.
The yield was almost quantitative | | Therapeutic Function | Antitubercular |
| | Pasiniazid Preparation Products And Raw materials |
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