- QUASSIN
-
-
2025-12-24
- CAS:76-78-8
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10
- QUASSIN
-
-
2024-04-12
- CAS:76-78-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 2000ton
- Quassin
-
- $7.00
-
2023-02-13
- CAS:76-78-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 30MT
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| | QUASSIN Basic information |
| Product Name: | QUASSIN | | Synonyms: | Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy-;QUASSINPOWDER;QUASSIN;11,16-trione,2,12-dimethoxy-picrasa-12-diene-1;(3aS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a;(3As,6ar,7as,8S,11as,11bs,11cs)-1,3A,4,5,6A,7,7A,8,11,11A,11B,11C-dodecahydro-2,10-dimethoxy-3,8,11A,11C-tetramethyldibenzo(de,G)chromene-1,5,11-trione;2,12-Dimethoxypicrasa-2,12-diene-1,11,16-trione;Einecs 200-985-9 | | CAS: | 76-78-8 | | MF: | C22H28O6 | | MW: | 388.45 | | EINECS: | 200-985-9 | | Product Categories: | | | Mol File: | 76-78-8.mol |  |
| | QUASSIN Chemical Properties |
| Melting point | 222° | | alpha | D20 +34.5° (c = 5.09 in CHCl3) | | Boiling point | 586.3±50.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Optical Rotation | +34.520 (c 5.09, CHCl3) | | Major Application | food and beverages | | Cosmetics Ingredients Functions | DENATURANT | | InChIKey | IOSXSVZRTUWBHC-LBTVDEKVSA-N | | SMILES | C1(=O)[C@]2([C@](C[C@@]3([C@@]4([C@@]2(C(=O)C(OC)=C(C)[C@]4([H])CC(=O)O3)[H])C)[H])([H])[C@H](C)C=C1OC)C | | LogP | 2.220 (est) | | EPA Substance Registry System | Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy- (76-78-8) |
| WGK Germany | WGK 3 | | TSCA | TSCA listed | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | QUASSIN Usage And Synthesis |
| Uses | Quassin is a naturally occurring extract from quassia trees and is used in traditional chinese medicine for its antiulcerogenic properties. Quassin have also been used as an additive in soft drinks. | | Definition | ChEBI: Quassin is a triterpenoid. | | in vivo | Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats[1]. | Animal Model: | 35 females albino rats (150-170 g)[1] | | Dosage: | 0.1 mg/kg, 1.0 mg/kg and 2.0 mg/kg | | Administration: | Oral administration; daily; for 60 days | | Result: | There was a significant decrease in the weight of the ovary and uterus in all the groups relative to the control. There was also a significant decrease in serum estrogen levels in quassin treated rats. |
| | IC 50 | Plasmodium |
| | QUASSIN Preparation Products And Raw materials |
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