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1-(6-nitropyridin-3-yl)piperazine

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Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:1-(6-nitropyridin-3-yl)piperazine
CAS:775288-71-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: career henan chemical co
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Products Intro: Product Name:1-(6-nitropyridin-3-yl)piperazine
CAS:775288-71-6
Purity:98% Package:1KG;1USD|1KG;1USD
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Products Intro: Product Name:1-(6-nitropyridin-3-yl)piperazine
CAS:775288-71-6
Purity:98% Package:5KG;1KG
Company Name: Accela ChemBio Inc.
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Products Intro: Product Name:1-(6-Nitro-3-pyridyl)piperazine
CAS:775288-71-6
Purity:95% Package:1g Remarks:SY061053
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Products Intro: Product Name:1-(6-nitropyridin-3-yl)piperazine
CAS:775288-71-6
Purity:0.98 Package:1kg，2kg，5kg，10kg，25kg

1-(6-nitropyridin-3-yl)piperazine manufacturers
1-(6-nitropyridin-3-yl)piperazine Basic information
Product Name:1-(6-nitropyridin-3-yl)piperazine
Synonyms:1-(6-nitropyridin-3-yl)piperazine;AKOS BBV-002250;OTAVA-BB 1314167;Piperazine, 1-(6-nitro-3-pyridinyl)-;1-(6-Nitro-3-pyridyl)piperazine;1-(6-Nitro-3-pyridinyl)piperazine;Xylulose Impurity 4
CAS:775288-71-6
MF:C9H12N4O2
MW:208.22
EINECS:
Product Categories:palbo
Mol File:775288-71-6.mol
1-(6-nitropyridin-3-yl)piperazine Structure
1-(6-nitropyridin-3-yl)piperazine Chemical Properties
Boiling point 422.8±40.0 °C(Predicted)
density 1.278±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform; Methanol
form Solid
pka8.50±0.10(Predicted)
color Yellow
Safety Information
MSDS Information
1-(6-nitropyridin-3-yl)piperazine Usage And Synthesis
Uses1-?(6-?Nitro-?3-?pyridinyl)?piperazine is a reagent used in the preparation of highly potent and orally bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine cyclin-dependant kinases as anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
1-(6-nitropyridin-3-yl)piperazine Preparation Products And Raw materials
Raw materials1-BOC-4-(6-NITROPYRIDIN-3-YL)PIPERAZINE-->5-Chloro-2-nitropyridine-->5-Bromo-2-nitropyridine-->Piperazine
Tag:1-(6-nitropyridin-3-yl)piperazine(775288-71-6) Related Product Information
tert-butyl 4-(4-aminopyridin-2-yl)piperazine-1-carboxylate 4-(5-AMINOPYRIDIN-2-YL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-Amino-2-[4-butoxycarbonyl(piperazino)]pyridine 4-(3-NITRO-PYRIDIN-2-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Palbociclib Impurity 61 1-Piperazinecarboxylic acid, 4-(4-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester INDEX NAME NOT YET ASSIGNED 1-BOC-4-(5-NITRO-2-PYRIDYL)PIPERAZINE 2324831-15-2 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester 5-(piperazin-1-yl)pyridin-2-aMine Palbociclib Impurity V tert-butyl 4-(3-nitropyridin-4-yl)piperazine-1-carboxylate 4-(6-Amino-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester 1-BOC-4-(3-AMINO-4-PYRIDINYL)-PIPERAZINE 1-(6-AMino-2,3-diMethoxy-phenyl)-ethanone Palbociclib Impurity 59 1-(3-Pyridinyl)piperazine