| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:H-1152 Glycyl Dihydrochloride
CAS:913844-45-8
Package:10Mg,1Mg
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| Company Name: |
VDM Biochemicals
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| Tel: |
0330-2528181 |
| Email: |
sales@vdmbio.com |
| Products Intro: |
Product Name:Glycyl-H 1152 dihydrochloride
CAS:913844-45-8
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| | H-1152Glycyl, Dihydrochloride Basic information |
| | H-1152Glycyl, Dihydrochloride Chemical Properties |
| Melting point | 190-192°C | | storage temp. | Refrigerator | | solubility | Methanol (Slightly), Water (Slightly) | | form | Solid | | color | Pale Yellow to Beige | | Stability: | Hygroscopic | | CAS DataBase Reference | 913844-45-8 |
| | H-1152Glycyl, Dihydrochloride Usage And Synthesis |
| Chemical Properties | Pale-Yellow Solid | | Uses | A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis. | | Biological Activity | Glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride ((S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride ) that displays improved ROCKII selectivity. IC 50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μ M for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively. | | storage | room temperature (desiccate) |
| | H-1152Glycyl, Dihydrochloride Preparation Products And Raw materials |
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