- Vatalanib base
-
- $1.00 / 100g
-
2019-12-24
- CAS:212141-54-3
- Min. Order: 100g
- Purity: 98%min
- Supply Ability: G/KG/T
- Vatalanib base
-
- $1.00 / 100g
-
2019-12-24
- CAS:212141-54-3
- Min. Order: 100g
- Purity: 98%min
- Supply Ability: G/KG/T
|
| | Vatalanib base Basic information |
| Product Name: | Vatalanib base | | Synonyms: | N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine;N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)- 1-Phthalazinamine;1-PhthalazinaMine, N-(4-chlorophenyl)-4-(4-pyridinylMethyl)-;Vatalanib (PTK787) Dihydrochloride Base;Pynasunate, ZK222584, CGP-79787, PTK 787;(4-Chloro-phenyl)-(4-pyridin-4-ylmethyl-phthalazin-1-yl)-amine;Vatalanib (free base);VATALANIB | | CAS: | 212141-54-3 | | MF: | C20H15ClN4 | | MW: | 346.81 | | EINECS: | | | Product Categories: | Antineoplastic | | Mol File: | 212141-54-3.mol |  |
| | Vatalanib base Chemical Properties |
| Melting point | 209-212° | | Boiling point | 587.8±50.0 °C(Predicted) | | density | 1.330±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic | | form | solid | | pka | 5.46±0.10(Predicted) |
| | Vatalanib base Usage And Synthesis |
| Uses | anti-viral | | Uses | Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively. | | Definition | ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit
r for all isoforms of VEGFR, PDGFR and c-Kit. |
| | Vatalanib base Preparation Products And Raw materials |
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