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Sigma-Aldrich
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| Products Intro: |
Product Name:Cordycepin 5'-triphosphate sodium salt
CAS:71997-32-5
Purity:>=95% Package:5MG Remarks:C9137-5MG
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| | 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Basic information |
| Product Name: | 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT | | Synonyms: | CORDYCEPIN 5'-TRIPHOSPHATE SODIUM SALT;3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT;cordycepin 5'-triphosphate sodium;3'-deoxyadenosine 5'-triphosphate;Cordycepin-5''-triphosphoric acid;3'-deoxyadenosine-5'-triphosphate sodium;Cordycepin 5′-triphosphate;Sodium (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-3-olate | | CAS: | 71997-32-5 | | MF: | C10H17N5NaO12P3 | | MW: | 515.18 | | EINECS: | | | Product Categories: | | | Mol File: | 71997-32-5.mol |  |
| | 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Chemical Properties |
| | 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Usage And Synthesis |
| Uses | Cordycepin 5′-triphosphate sodium salt has been used:
- as a transcriptional inhibitor in RNA decay assay
- to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
- as a positive control in in vitro assays for polymerase inhibition
- as a precursor to produce cordycepin monophosphate
| | Definition | ChEBI: Cordycepin triphosphate is a purine ribonucleoside 5'-triphosphate. It has a role as an antimetabolite, an antifungal agent, an antineoplastic agent and an antiviral agent. It is functionally related to a cordycepin. | | General Description | Cordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin. | | Biochem/physiol Actions | Cordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis. |
| | 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Preparation Products And Raw materials |
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