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| | ANTI-HUMAN CD31 Basic information |
| Product Name: | ANTI-HUMAN CD31 | | Synonyms: | ANTI-CD31, PECAM-1;ANTI-CD31, HUMAN (WS VI);ANTI-CD31;ANTI-CD31 (HUMAN);ANTI-CD31 (HUMAN)-CLONE MEM-05;ANTI-CD31, HUMAN, ENDOTHELIAL CELLS;ANTI-GPLLA;ANTI-HUMAN PLATELET GLYCOPROTEIN IIA+ (GPLLA) PECAM | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN CD31 Structure]() |
| | ANTI-HUMAN CD31 Chemical Properties |
| storage temp. | 2-8°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 |
| | ANTI-HUMAN CD31 Usage And Synthesis |
| Uses | Monoclonal Anti-CD31 (PECAM-1)-FITC antibody has been used in
- DAB based-immunohistochemistry
- direct immunofluorescent staining
- fluorescence-activated cell sorting (FACS)
- flow cytometry
| | General Description | CD31 is a single chain integral membrane glycoprotein member of the immunoglobulin superfamily of cell adhesion molecules with molecular mass of 130-140kDa. It has six Ig-like loops in the extracellular domain, a trans-membrane domain including a relatively long cytoplasmic domain. It is expressed abundantly on platelets, myeloid cells, B lymphocytes, certain T-lymphocyte cell subsets, bone marrow precursor cells, NK cells and localized to the intracellular junctions in monolayers of cultured endothelial cells. | | Biochem/physiol Actions | CD31 is also known as PECAM-1 (Platelet endothelial cell adhesion molecule-1) binds to glycosaminoglycans (GAG). Endothelial CD31 is phosphorylated on tyrosine and serine residues. CD31 is involved in some of the interactive events taking place during cardiovascular development inflammation, thrombosis, wound healing and angiogenesis. |
| | ANTI-HUMAN CD31 Preparation Products And Raw materials |
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