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| | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Basic information |
| Product Name: | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE | | Synonyms: | DIHYDRO-3-HYDROXY-2(3H)-FURANONE;3-HYDROXYTETRAHYDROFURAN-2-ONE;AKOS 224;ALPHA-HYDROXY-GAMMA-BUTYROLACTONE;4,5-Dihydro-3-hydroxy-2(3H)-furanone;α-Hydroxy-γ-butyrolactone;4,5-Dihydroxy-3-hydroxy-2(3H)-furanone;ALPHA-HYDROXY-GAMMA-BUTYROLACTONE, TECH. | | CAS: | 19444-84-9 | | MF: | C4H6O3 | | MW: | 102.09 | | EINECS: | | | Product Categories: | | | Mol File: | 19444-84-9.mol |  |
| | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties |
| Boiling point | 133 °C/10 mmHg (lit.) | | density | 1.309 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.468(lit.) | | Fp | >230 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | pka | 13.07±0.20(Predicted) | | form | Viscous Liquid | | color | Clear colorless to yellow | | BRN | 80587 | | InChIKey | FWIBCWKHNZBDLS-UHFFFAOYSA-N | | LogP | -1.830 (est) | | CAS DataBase Reference | 19444-84-9(CAS DataBase Reference) |
| | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Usage And Synthesis |
| Chemical Properties | clear colorless to yellow viscous liquid | | Uses | α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction. | | Uses | α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. 1 It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction. | | General Description | α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. | | Purification Methods | It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox |
| | ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Preparation Products And Raw materials |
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