- Cyclopropyl acetylene
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- $10.00 / 1KG
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2026-03-20
- CAS:6746-94-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- Cyclopropyl acetylene
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- $0.00 / 30kg
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2025-06-20
- CAS:6746-94-7
- Min. Order: 9kg
- Purity: 99%
- Supply Ability: 9MT/20FCL;50MT/Month
- Ethynylcyclopropane
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- $786.00 / 1Kg
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2025-04-09
- CAS:6746-94-7
- Min. Order: 0.100Kg
- Purity: 99 %
- Supply Ability: 5000 Kg
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| | Cyclopropylacetylene Basic information |
| | Cyclopropylacetylene Chemical Properties |
| Melting point | 294 °C (decomp) | | Boiling point | 79-80 °C | | density | 0.7801 | | refractive index | n20/D 1.4480 | | Fp | -5 °F | | storage temp. | 2-8°C | | solubility | Chloroform, Ethyl Acetate | | form | Liquid | | Specific Gravity | 0.797 | | color | Clear colorless to light yellow | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C5H6/c1-2-5-3-4-5/h1,5H,3-4H2 | | InChIKey | NPTDXPDGUHAFKC-UHFFFAOYSA-N | | SMILES | C1(C#C)CC1 | | CAS DataBase Reference | 6746-94-7(CAS DataBase Reference) | | NIST Chemistry Reference | Cyclopropylacetylene(6746-94-7) |
| | Cyclopropylacetylene Usage And Synthesis |
| Preparation | Cyclopropylacetylene was prepared in a two-step procedure by dichlorination of cyclopropyl methyl ketone with phosphorus pentachloride (PCl5) followed by double dehydrohalogenation with a strong base. This sequence presented significant scale-up problems with low overall yields (20-25%).
Similarly, cyclopropylacetylene has been prepared by base-induced dehydrohalogenation of bromovinylcyclopropane . Cyclopropylacetylene has also been prepared from the 1-trimethylsilyl derivative of cyclopropylacetylene, which was prepared by treatment of 5-chloro-1-trimethylsilyl-1-pentyne with lithium diisopropylamide at 78°C followed by warming to room temperature. | | Chemical Properties | clear colorless to light yellow liquid | | Uses | Cyclopropylacetylene is used as an organic chemical synthesis intermediate. | | Synthesis | The general procedure for synthesizing cyclopropylacetylene from (1,1-dichloroethyl)cyclopropane was as follows: 1) 80 g of sodium hydroxide was mixed with 300 mL of ethoxyethanol and stirred at -60 °C, followed by the slow addition of 100 g of chlorocyclopropylacetylene at the same temperature. After the reaction was completed (the reaction process was monitored by gas chromatography analysis), atmospheric pressure distillation was performed to collect the 55 °C-65 °C fraction to obtain crude cyclopropylacetylene; 2) The crude cyclopropylacetylene was purified by distillation with continuous stirring. Finally, 59 g of cyclopropylacetylene with a purity greater than 98% was obtained, with a yield of 89%. | | References | [1] Patent: CN105985223, 2016, A. Location in patent: Paragraph 0049; 0050; 0051; 0052
[2] Journal of Organic Chemistry, 1976, vol. 41, # 7, p. 1237 - 1240
[3] Synthesis, 1972, p. 703
[4] Journal of the American Chemical Society, 1972, vol. 94, p. 1158 - 1163
[5] Synlett, 1999, # 12, p. 1948 - 1950 |
| | Cyclopropylacetylene Preparation Products And Raw materials |
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