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| | 1-Bromo-2-(2-methoxyethoxy)ethane Basic information |
| Product Name: | 1-Bromo-2-(2-methoxyethoxy)ethane | | Synonyms: | 1-BROMO-2-(2-METHOXYETHOXY)ETHANE;MONO METHOXY PEG BROMIDE;Ethane, 1-(2-bromoethoxy)-2-methoxy-;1-BROMO-2-(2-METHOXYETHOXY)ETHANE, TECH. 90%, STAB. WITH SOD;1-BROMO-(2-METHOXYETHOXY)ETHANE;1-Bromo-2-(2-methoxyethoxy)ethane, tech. 90%, stab. with sodium carbonate;1-Bromo-2-(2-methoxyethoxy)ethane, tech. 90%;1-bromo-3,6-dioxaheptane | | CAS: | 54149-17-6 | | MF: | C5H11BrO2 | | MW: | 183.04 | | EINECS: | 259-000-6 | | Product Categories: | Ethers;Organic Building Blocks;Oxygen Compounds | | Mol File: | 54149-17-6.mol |  |
| | 1-Bromo-2-(2-methoxyethoxy)ethane Chemical Properties |
| Boiling point | 156 °C (lit.)
37-40 °C/0.01 mmHg (lit.) | | density | 1.3600 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.455(lit.) | | Fp | 163 °F | | storage temp. | 2-8°C | | form | Liquid | | color | Clear colorless to pale yellow | | Water Solubility | Not miscible in water. | | Sensitive | Light Sensitive | | BRN | 2069579 | | InChI | InChI=1S/C5H11BrO2/c1-7-4-5-8-3-2-6/h2-5H2,1H3 | | InChIKey | HUXJXNSHCKHFIL-UHFFFAOYSA-N | | SMILES | C(OCCBr)COC | | CAS DataBase Reference | 54149-17-6(CAS DataBase Reference) | | NIST Chemistry Reference | 1-Bromo-2-(2-methoxyethoxy)ethane(54149-17-6) |
| Risk Statements | 36/37/38 | | Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29091990 |
| | 1-Bromo-2-(2-methoxyethoxy)ethane Usage And Synthesis |
| Chemical Properties | clear colorless to pale yellow liquid | | Uses | 1-Bromo-2-(2-methoxyethoxy)ethane is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Synthesis | General Procedure for Preparation of 1-Bromo-2-(2-methoxyethoxy)ethane: Into a 25-mL round bottomed flask equipped with magnetic stir bar, addition funnel and positive flow of nitrogen were placed 15.60 mmol of a ethyleneglycol monomethyl ether. The solution was stirred for 15 min in an ice bath before the dropwise addition of phosphorous tribromide (7.81 mmol) over a 10 min period. The solution was allowed to gradually warm and stir at room temperature (rt) for 14 hrs. The solution was then heated in a 90 °C oil bath for 1 hr, at which time the solution turned yellow. The solution was allowed to cool to rt, poured onto 30 g of ice/water mixture, and made slightly basic with addition of a 10% solution of NaHCO3 (~6 mL). Subsequent extraction with diethyl ether (Et2O) (3 x 30 mL), followed by drying over MgSO4 and concentration under reduced pressure afforded a colorless oil in sufficient purity for use in subsequent reactions.
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| | 1-Bromo-2-(2-methoxyethoxy)ethane Preparation Products And Raw materials |
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