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| | 2-Trifluoromethylphenylboronic acid Basic information |
| | 2-Trifluoromethylphenylboronic acid Chemical Properties |
| Melting point | 111-114 °C (lit.) | | Boiling point | 274.5±50.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | slightly sol. in Methanol | | form | powder to crystal | | pka | 8.11±0.58(Predicted) | | color | White to Almost white | | BRN | 2974465 | | InChIKey | JNSBEPKGFVENFS-UHFFFAOYSA-N | | CAS DataBase Reference | 1423-27-4(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29163990 |
| | 2-Trifluoromethylphenylboronic acid Usage And Synthesis |
| Chemical Properties | white to light beige crystalline powder | | Uses | 2-(Trifluoromethyl)phenylboronic acid can be used as a reactant:
- In Suzuki-coupling reactions to prepare 2-trifluoromethyl aryl or heteroaryl derivatives.
- To synthesize 4-(2-trifluoromethyl)phenylpyrrolo[2,3-d]pyrimidine as a potential antagonist of corticotropin-releasing hormone.
- To prepare 2-nitro-6-(trifluoromethyl)phenylboronic acid by nitration reaction.
| | Uses | suzuki reaction | | Uses | 2-Trifluoromethylphenylboronic Acid is a reagent in the preparation of potent inhibitors of human uric acid transporter 1 (hURAT1). |
| | 2-Trifluoromethylphenylboronic acid Preparation Products And Raw materials |
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