| Company Name: |
Nanjing Tengyi Biotechnology Co., Ltd
|
| Tel: |
025-58851786 17714337195 |
| Email: |
sales@tybiochem.com |
| Products Intro: |
Product Name:RG-13022
CAS:149286-90-8
Purity:95+% Package:1g;5g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:RG-13022
CAS:149286-90-8
Purity:98% Package:5mg;10mg;50mg
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:RG-13022
CAS:149286-90-8
Package:>98% Remarks:10010309
|
|
| | RG-13022 Basic information |
| Product Name: | RG-13022 | | Synonyms: | 3-Pyridineacetonitrile, α-[(3,4-dimethoxyphenyl)methylene]-, (αZ)- | | CAS: | 149286-90-8 | | MF: | C16H14N2O2 | | MW: | 266.29456 | | EINECS: | | | Product Categories: | | | Mol File: | 149286-90-8.mol |  |
| | RG-13022 Chemical Properties |
| Boiling point | 423.8±45.0 °C(Predicted) | | density | 1.172±0.06 g/cm3(Predicted) | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml | | form | A crystalline solid | | pka | 3.74±0.12(Predicted) |
| | RG-13022 Usage And Synthesis |
| Description | Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. RG-13022 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 1 μM in HT-22 cells. | | Definition | ChEBI: 3-(3,4-dimethoxyphenyl)-2-(3-pyridinyl)-2-propenenitrile is a dimethoxybenzene. |
| | RG-13022 Preparation Products And Raw materials |
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