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AM-1220

AM-1220 Basic information
Product Name:AM-1220
Synonyms:AM-1220;Methanone, [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-;(1-((1-Methylpiperidin-2-yl)Methyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone;[1-[(1-Methyl-2-piperidinyl)Methyl]-1H-indol-3-yl]-1-naphthalenylMethanone;[1-[(1-methylpiperidin-2-yl)methyl]indol-3-yl]-naphthalen-1-ylmethanone
CAS:137642-54-7
MF:C26H26N2O
MW:382.5
EINECS:
Product Categories:Amines;Heterocycles;Indole Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Research Chemical;Chemical for Research
Mol File:137642-54-7.mol
AM-1220 Structure
AM-1220 Chemical Properties
Boiling point 575.6±20.0 °C(Predicted)
density 1.17
solubility DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.15 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka9.75±0.10(Predicted)
Safety Information
MSDS Information
AM-1220 Usage And Synthesis
DescriptionAM1220 is a potent synthetic cannabinoid (CB) with preference for the central CB1 receptor (Ki = 3.88 nM) over the CB2 receptor (Ki = 73.4 nM). The physiological actions and metabolism of AM1220 have not been characterized.
UsesAM-1220 is a synthetic cannabimimetic indole derivative. AM-1220 acts as a potent and moderately selective agonist for the cannabinoid receptor CB1 with around 19 times the selectivity for CB1 over CB2 receptor.
AM-1220 Preparation Products And Raw materials
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