Log in | Join Free | china | japan | germany
ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >1-N-Boc-4-(Phenylamino)piperidine

1-N-Boc-4-(Phenylamino)piperidine

1-N-Boc-4-(Phenylamino)piperidine Basic information
Product Name:1-N-Boc-4-(Phenylamino)piperidine
Synonyms:TERT-BUTYL 4-ANILINOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE;1-N-BOC-4-(PHENYLAMINO)PIPERIDINE;tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate (en);N-tert-Butoxycarbonyl-4-anilinopiperidine;1-N-Boc-4-(Phenylamino)piperidine - 97.0%;1-(tert-Butyloxycarbonyl)-4-(phenylaMino)piperidine;4-(PhenylaMino)-1-piperidinecarboxylic Acid 1,1-DiMethylethyl Ester;tert-Butyl 4-(phenylamino)piperidine-1-carboxylate, tert-Butyl 4-anilinopiperidine-1-carboxylate
CAS:125541-22-2
MF:C16H24N2O2
MW:276.37
EINECS:203-105-0
Product Categories:Intermediates;inter;Aromatics;Heterocycles;pharmaceutical;Intermediate;125541-22-2;Pharm
Mol File:125541-22-2.mol
1-N-Boc-4-(Phenylamino)piperidine Structure
1-N-Boc-4-(Phenylamino)piperidine Chemical Properties
Melting point 136-137
Boiling point 400.6±38.0 °C(Predicted)
density 1.107±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 15mg/mL; DMSO: 25mg/mL; Ethanol: 25mg/mL; Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL
form A crystalline solid
pka5.00±0.20(Predicted)
InChIInChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3
InChIKeyHTIWISWAPVQGMI-UHFFFAOYSA-N
SMILESN1(C(OC(C)(C)C)=O)CCC(NC2=CC=CC=C2)CC1
Safety Information
Hazard Codes Xi,Xn
Risk Statements 22
Hazard Note Harmful/Irritant
HazardClass IRRITANT
HS Code 2933399990
MSDS Information
1-N-Boc-4-(Phenylamino)piperidine Usage And Synthesis
Description4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.
Chemical PropertiesPale Brown Solid
UsesIntermediate in the preparation of Fentanyl derivatives.
Application1-N-Boc-4-(Phenylamino)piperidine is an amino acid derivative widely employed as a reagent in organic synthesis. This compound exhibits remarkable versatility, finding applications in various fields such as peptide and protein synthesis, organic synthesis, and drug development. It possesses strong basic properties, allowing for diverse reactions with acids that lead to the formation of a wide array of products. The extensive use of this compound in organic synthesis is well-documented, particularly in the synthesis of peptides and proteins. By facilitating the coupling of amino acids, it enables the creation of peptides that can be utilized in diverse applications, including the development of pharmaceutical drugs.
1-N-Boc-4-(Phenylamino)piperidine Preparation Products And Raw materials
Preparation ProductsN-phenylpiperidin-4-amine-->N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE
Tag:1-N-Boc-4-(Phenylamino)piperidine(125541-22-2) Related Product Information
tert-Butyl acetoacetate N-Methylaniline tert-Butyl acetate tert-Butyl bromoacetate N-Phenylglycinonitrile 4-NITRODIAZOAMINOBENZENE tert-Butyl methacrylate tert-Butyl peroxyacetate tert-Butyl chloroacetate tert-Butyl acrylate DL-Phenylalanine Haloperidol N-BOC-4-METHYL-4-HYDROXY PIPERIDINE tert-butyl 4-(2-bromo-5-fluoropyridin-4-yl)-4-hydroxypiperidine-1-carboxylate tert-butyl 4-(2-aminoethyl)-3,3-difluoropiperidine-1-carboxylate 4-(3-AMINO-PHENYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER TERT-BUTYL 4-BROMOBENZYLCARBAMATE 1-Boc-4-(2-hydroxyethyl)piperidine