| Company Name: |
NCE Biomedical Co.,Ltd. |
| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Email: |
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| Company Name: |
Cckinase, Inc. |
| Tel: |
+1 (732)236-3202 |
| Email: |
sales@cckinase.com |
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| Product Name: | XL-647 | | Synonyms: | 4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aa,5a,6aa)-octahydro- 2-met;CS-197;4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-;N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-4-quinazolinamine;7-{[(3aR,6aS)-2-Methyl-octahydrocyclopenta[c]pyrrol-5-yl]methoxy}-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine | | CAS: | 651031-01-5 | | MF: | C24H25Cl2FN4O2 | | MW: | 491.39 | | EINECS: | | | Product Categories: | | | Mol File: | 651031-01-5.mol |  |
| | XL-647 Chemical Properties |
| | XL-647 Usage And Synthesis |
| Uses | N-(3,4-Dichloro-2-fluorophenyl)-6-methoxy-7-[[(3aα,5α,6aα)-octahydro-2-methylcyclopenta[c]pyrrol-5-yl]methoxy]-4-quinazolinamine is an isomer of XL 647 (X746318) is a potent and selective EGFR phosphorylation inhibitor. | | Uses | XL647 is a novel spectrum-selective kinase inhibitor for EGFR, ErbB2, KDR, Flt-4 and EphB4 with IC50 of 0.3 nM, 16 nM, 1.5 nM, 8.7 nM and 1.4 nM, respectively. |
| | XL-647 Preparation Products And Raw materials |
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