索菲布韦杂质
| 中文名称 | 索菲布韦杂质 |
|---|---|
| 中文同义词 | 索非布韦杂质09;索非布韦杂质F;索福斯布韦杂质5;索菲布韦杂质F;索非司布韦国际药典杂质C;L-ALANINE, N-[(S)-HYDROXYPHENOXYPHOSPHINYL]-, 1-METHYLETHYL ESTER, (P鈫?'),(P'鈫?')-DIESTER WITH (2'R)-2'-DEOXY-2'-FLUORO-2'-METHYLURIDINE;索非布韦 3',5'-双-(S)-磷酸盐;索福斯布韦杂质33 |
| 英文名称 | L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 1-Methylethyl ester, (P→3'),(P'→5')-diester with (2'R)-2'-deoxy-2'-fluoro-2'-Methyluridine |
| 英文同义词 | Sofosbuvir Dimer;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir impurity F;Sofosbuvir 3’,5’-Bis-(S)-phosphate;(2S)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate;Sofosbuvir impurity 19/Sofosbuvir 3',5'-Bis-O-Phosphoramidate//Isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alanite;isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosph |
| CAS号 | 1337482-17-3 |
| 分子式 | C34H45FN4O13P2 |
| 分子量 | 798.69 |
| EINECS号 | |
| 相关类别 | 对照品-杂质对照品 |
| Mol文件 | 1337482-17-3.mol |
| 结构式 |  |
索菲布韦杂质 性质
| 密度 | 1.37±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.39±0.10(Predicted) |
| 颜色 | 浅黄至黄色 |
索菲布韦杂质 是 Sofosbuvir 的非对映异构体，是 Sofosbuvir 的杂质。Sofosbuvir (PSI-7977) 是 HCV RNA复制的抑制剂，表现出有效的抗丙型肝炎病毒活性。
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-I0406 | 索菲布韦杂质 Sofosbuvir impurity F | 1337482-17-3 | 1mg | 6800元 |
| 2023/03/20 | HY-I0406 | 索菲布韦杂质 Sofosbuvir impurity F | 1337482-17-3 | 5mg | 35000元 |