| Company Name: |
ShangHai Biochempartner Co.,Ltd
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| Tel: |
17754423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:DAP-81
CAS:794466-17-4
Purity:98% HPLC LCMS Package:100mg;1g
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| Company Name: |
Chunchuang (Wuhan) Technology Co., Ltd
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| Tel: |
15342225168 |
| Email: |
yutianchun2007@126.com |
| Products Intro: |
Product Name:DAP-81
CAS:794466-17-4
Purity:97%~99% HPLC Package:1mg;1g;10g;100g;1Kg;10Kg;100Kg;1T
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| Product Name: | DAP-81 | | Synonyms: | DAP-81;Acetamide, N-[4-[[4-[(2-benzoylphenyl)amino]-5-nitro-2-pyrimidinyl]amino]phenyl]- | | CAS: | 794466-17-4 | | MF: | C25H20N6O4 | | MW: | 468.46 | | EINECS: | | | Product Categories: | | | Mol File: | 794466-17-4.mol |  |
| | DAP-81 Chemical Properties |
| | DAP-81 Usage And Synthesis |
| Description | DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. |
| | DAP-81 Preparation Products And Raw materials |
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