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| | 7-CHLORO-1-HYDROXYISOQUINOLINE Basic information |
| Product Name: | 7-CHLORO-1-HYDROXYISOQUINOLINE | | Synonyms: | 7-Chloro-1(2H)-isoquinolinone;7-CHLORO-1-HYDROXYISOQUINOLINE;7-CHLORO-1(2H)-ISOQUINOLONE;7-Chloroisoquinolin-1-ol;7-chloro-2H-isoquinolin-1-one;1(2H)-Isoquinolinone, 7-chloro- | | CAS: | 24188-74-7 | | MF: | C9H6ClNO | | MW: | 179.6 | | EINECS: | | | Product Categories: | | | Mol File: | 24188-74-7.mol |  |
| | 7-CHLORO-1-HYDROXYISOQUINOLINE Chemical Properties |
| Melting point | 245-247 °C(Solv: methanol (67-56-1)) | | Boiling point | 414.9±45.0 °C(Predicted) | | density | 1.339±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 11.99±0.20(Predicted) |
| | 7-CHLORO-1-HYDROXYISOQUINOLINE Usage And Synthesis |
| Uses | 7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists. |
| | 7-CHLORO-1-HYDROXYISOQUINOLINE Preparation Products And Raw materials |
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