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beta-Diphosphopyridine nucleotide

beta-Diphosphopyridine nucleotide Suppliers list
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:NAD+
CAS:53-84-9
Purity:500KG Package:1KG;USD
Company Name: Casorganics US Corp
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Email: sales@casorganics.com
Products Intro: Product Name:beta-Diphosphopyridine nucleotide
CAS:53-84-9
Purity:99.8 Package:1KG;USD|5KG;USD|25KG;USD
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Nicotinamide adenine dinucleotide(NAD+)mono sodium salt
CAS:53-84-9
Purity:98%%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:beta-Diphosphopyridine nucleotide
CAS:53-84-9
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:53-84-9
CAS:53-84-9
Purity:0.99 Package:25KG,5KG;1KG;500G

Lastest Price from beta-Diphosphopyridine nucleotide manufacturers

  • NAD+
  • US $0.00 / KG
  • 2019-09-09
  • CAS:53-84-9
  • Min. Order: 10g
  • Purity: 500KG
  • Supply Ability: 98% HPLC
beta-Diphosphopyridine nucleotide Basic information
Product Name:beta-Diphosphopyridine nucleotide
Synonyms:B-NICOTINAMIDE ADENINE DINUCLEOTIDE*SIGM AULTRA FROM;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE M ONOHYDRATE F.YEAST;B-NICOTINAMIDE ADENINE DINUCLEOTIDE*FROM YEAST;BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE D IHYDRATE F. YEAST;B-NICOTINAMIDE ADENINE DINUCLEOTIDE*99+% CRYSTALLIN;B-Nicotinamide Adenine DinucleotideCrystalline;B-Nicotinamide Adenine DinucleotideOxidized Free;Nad(3-NicotinamideAdenineDinucleotide),Trihydrate
CAS:53-84-9
MF:C21H27N7O14P2
MW:663.43
EINECS:200-184-4
Product Categories:Bioproducts;Cofactor;Biochemistry;Enzymes and Coenzymes in Nucleic Acids;Nucleosides, Nucleotides & Related Reagents;Vitamin Related Compounds;Vitamins;nucleoside;Inhibitors
Mol File:53-84-9.mol
beta-Diphosphopyridine nucleotide Structure
beta-Diphosphopyridine nucleotide Chemical Properties
Melting point 140-142 °C (decomp)
alpha D20 -31.5° (c = 1.2 in water)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form Powder
color White
OdorOdorless
PH~3.0 (50mg/mL in water)
Water Solubility Soluble in water at 50mg/ml
Merck 14,6344
BRN 3584133
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKeyBAWFJGJZGIEFAR-WWRWIPRPSA-N
EPA Substance Registry SystemAdenosine 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, inner salt (53-84-9)
Safety Information
Hazard Codes Xn,F,Xi
Risk Statements 36-68/20/21/22-20/21/22-40-22
Safety Statements 36-26-36/37-24/25
WGK Germany 3
RTECS UU3450000
TSCA Yes
HS Code 29349990
MSDS Information
ProviderLanguage
beta-NAD English
beta-Diphosphopyridine nucleotide Usage And Synthesis
Chemical PropertiesBeta-NICOTINAMIDE ADENINE DINUCLEOTIDE is Hygroscopic white powder.
Usesantidepressant, oxytocic
Usesβ-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a c oenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleot ide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
DefinitionThe oxidized form of β-Nicotinamide Adenine Dinucleotide. It exists as an anion under normal physio-logic conditions.
Purification MethodsNAD is purified by paper chromatography or better on a Dowex-1 ion-exchange resin. The column is prepared by washing with 3M HCl until free of material absorbing at 260nm, then with water, 2M sodium formate until free of chloride ions and, finally, with water. NAD, as a 0.2% solution in water, is adjusted with NaOH to pH 8, and adsorbed onto the column, washed with water, and eluted with 0.1M formic acid. Fractions with strong absorption at 360nm are combined, acidified to pH 2.0 with 2M HCl, and cold acetone (ca 5L/g of NAD) is added slowly and with constant agitation. It is left overnight in the cold, then the precipitate is collected in a centrifuge, washed with pure acetone and dried under vacuum over CaCl2 and paraffin wax shavings [Kornberg Methods Enzymol 3 876 1957]. It has been purified by anion-exchange chromatography [Dalziel & Dickinson Biochemical Preparations 11 84 1966.] The purity is checked by reduction to NADH (with EtOH and yeast alcohol dehydrogenase) which has 340mn 6220 M-1cm-1. [Todd et al. J Chem Soc 3727, 3733 1957.] [pKa, Lamborg et al. J Biol Chem 231 685 1958.] The free acid crystallises from aqueous Me2CO with 3H2O and has m 140-142o. It is stable in cold neutral aqueous solutions in a desiccator (CaCl2) at 25o, but decomposes at strong acid and alkaline pH. Its purity is checked by reduction with yeast alcohol dehydrogenase and EtOH to NADH and noting the OD at 340nm. Pure NADH (see below) has 340 6.2 x 104 M-1cm-1, i.e. 0.1mole of NADH in 3mL and in a 1cm path length cell has an OD at 340nm of 0.207. [Beilstein 26 IV 3644.]
Tag:beta-Diphosphopyridine nucleotide(53-84-9) Related Product Information
2':3'-CYCLIC NADP SODIUM SALT NICOTINAMIDE ADENINE DINUCLEOTIDE-AGAROSE 3'-NADP SODIUM SALT BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE SODIUM SALT BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE RESIN NAD 3H2O β-Nicotinamide adenine dinucleotide phosphate sodium salt BETA-NAD TETRAHYDRATE NADP MONOPOTASSIUM SALT NAD3H DIPOTASSIUM SALT BETA-DIPHOSPHOPYRIDINE NUCLEOTIDE, OXIDIZED FORM N6-([6-AMINOHEXYL]-CARBAMOYLMETHYL)-NICOTINAMIDE ADENINE DINUCLEOTIDE LITHIUM SALT NICOTINAMIDE ADENINE DINUCLEOTIDE, [ADENYLATE-32P] DIPOTASSIUM SALT Triphosphopyridine nucleotide disodium salt BETA-DIPHOSPHOPYRIDINE NUCLEOTIDE HYDRATE, OXIDIZED FORM,BETA-DIPHOSPHOPYRIDINE NUCLEOTIDE OXIDIZED FORM, HYDRATE beta-Diphosphopyridine nucleotide 6-Thioguanine 2,3-Dimethoxy-5-methyl-p-benzoquinone