Company Name: |
Borenpharm Co., Ltd
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Tel: |
027-65563561 |
Email: |
sales@borenpharm.com |
Products Intro: |
Product Name:MS-PEG4-THP CAS:145927-73-7 Purity:95% HPLC Package:1g; 5g Remarks:509.5g
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| Mes-PEG5- THP Basic information |
Product Name: | Mes-PEG5- THP | Synonyms: | Mes-PEG5- THP;Mes-PEG4- THP;MS-PEG4-THP;CAS_145927-73-7;Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 1-methanesulfonate;MSPEG4THP,MS-PEG-4-THP,PROTAC Linkers,inhibit,MS PEG4 THP,Inhibitor;2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl methanesulfonate | CAS: | 145927-73-7 | MF: | C14H28O8S | MW: | 356.43 | EINECS: | | Product Categories: | | Mol File: | 145927-73-7.mol | |
| Mes-PEG5- THP Chemical Properties |
form | Liquid | color | Light yellow to light brown |
| Mes-PEG5- THP Usage And Synthesis |
Biological Activity | MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Mes-PEG5- THP Preparation Products And Raw materials |
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