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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester

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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:C6-Bis-phosphoramidic acid diethyl ester
CAS:1446282-35-4
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:C6-Bis-phosphoramidic acid diethyl ester
CAS:1446282-35-4
Purity:95%+ Remarks:MC739326
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203
Email: info@chemextension.com
Products Intro: Product Name:6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
CAS:1446282-35-4
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Aladdin Scientific
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Products Intro: Product Name:[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
CAS:1446282-35-4
Purity:96% Package:$781.9/250mg;$1141.9/500mg;$1741.9/1g;Bulk package Remarks:96%
Company Name: Jinan elephant international trading co., LTD  
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Products Intro: Product Name:[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
Purity:99% HPLC Package:5KG;1KG
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Basic information
Product Name:[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
Synonyms:[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester;C6-Bis-phosphoramidic acid diethyl ester
CAS:1446282-35-4
MF:C14H34N2O6P2
MW:388.38
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Mol File:1446282-35-4.mol
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Structure
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Chemical Properties
Boiling point 442.2±55.0 °C(Predicted)
density 1.106±0.06 g/cm3(Predicted)
pka2.06±0.70(Predicted)
Safety Information
MSDS Information
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Usage And Synthesis
Biological ActivityC6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Preparation Products And Raw materials
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