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| | Azdo-PEG3-S-PEG3-Azide Basic information |
| Product Name: | Azdo-PEG3-S-PEG3-Azide | | Synonyms: | Azdo-PEG3-S-PEG3-Azide;Azido-PEG3-S-PEG3-azide;N3-PEG3-S-PEG3-N3;3,6,9,15,18,21-Hexaoxa-12-thiatricosane, 1,23-diazido- | | CAS: | 2055023-77-1 | | MF: | C16H32N6O6S | | MW: | 436.52688 | | EINECS: | | | Product Categories: | | | Mol File: | 2055023-77-1.mol |  |
| | Azdo-PEG3-S-PEG3-Azide Chemical Properties |
| | Azdo-PEG3-S-PEG3-Azide Usage And Synthesis |
| Description | Azido-PEG3-S-PEG3-azide is a PEG linker containing two azide groups. The azide group enables Click Chemistry with alkyne, DBCO and BCN moieties. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Azido-PEG3-S-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-S-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | Azdo-PEG3-S-PEG3-Azide Preparation Products And Raw materials |
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