Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 Suppliers list

Company Name:	ATK CHEMICAL COMPANY LIMITED
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Email:	ivan@atkchemical.com
Products Intro:	Product Name:LY2510924 CAS:1088715-84-7 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G

Company Name:	Shenzhen Nexconn Pharmatechs Ltd
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Products Intro:	Product Name:LY2510924 CAS:1088715-84-7 Purity:98% Package:1KG;10KG;50KG

Company Name:	BOC Sciences
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Products Intro:	Product Name:LY-2510924 CAS:1088715-84-7 Purity:98% Package:5 mg Remarks:Reach out to us for more information about custom solutions.

Company Name:	Shanghai Longyu Biotechnology Co., Ltd.
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Products Intro:	Product Name:LY-2510924 CAS:1088715-84-7 Purity:0.99 Package:100gram;1kilo;5kilo;482kilo Remarks:Accept Paypal/western union/bitcoin/money gram/alibaba trade assurance

Company Name:	career henan chemical co
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Products Intro:	Product Name:Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2A CAS:1088715-84-7 Purity:99% Package:1KG;7USD

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 manufacturers

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2A
$7.00 / 1KG
2020-02-13
CAS:1088715-84-7
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 Basic information

Product Name:	Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2
Synonyms:	Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2;LY2510924;LY2510924; LY-2510924; LY 2510924;CS-2675;Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2A;L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7→1)-lactam;(2S,5S,8S,11R,14S,20R)-N-((S)-1-Amino-6-(isopropylamino)-1-oxohexan-2-yl)-2-benzyl-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-8-(4-(isopropylamino)butyl)-14-(naphthalen-2-ylmethyl)-3,6,9,12,15,18,23-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosane-20-carboxamide;LY2510924 TFA salt
CAS:	1088715-84-7
MF:	C62H88N14O10
MW:	1189.47
EINECS:
Product Categories:
Mol File:	1088715-84-7.mol

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 Chemical Properties

density	1.33±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 125 mg/mL (105.09 mM)
form	Solid
pka	9.89±0.15(Predicted)
color	White to off-white
InChIKey	IJHWVENTEFSNBC-QBSDWBABNA-N

Safety Information

MSDS Information

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 Usage And Synthesis

Uses	LY2510924 is a CXC chemokine receptor 4 inhibitor and a potential antineoplastic agent.
in vivo	LY2510924 specifically blocks SDF-1 binding to CXCR4 with IC₅₀ value of 0.079 nM, and inhibits SDF-1–induced GTP binding with K_b value of 0.38 nM. In human lymphoma U937 cells expressing endogenous CXCR4, LY2510924 inhibits SDF-1–induced cell migration with IC₅₀ value of 0.26 nM and inhibits SDF-1/CXCR4-mediated intracellular signaling. LY2510924 exhibits a concentration-dependent inhibition of SDF-1–stimulated phospho-ERK and phospho-Akt in tumor cells. Biochemical and cellular analyses reveals that LY2510924 has no apparent agonist activity^[1]. LY2510924 chiefly inhibits the proliferation of AML cells with little induction of cell death and reduces protection against chemotherapy by stromal cells^[2].
IC 50	¹²⁵I-SDF-1α-CXCR4: 79.7 pM (IC₅₀); ¹²⁵I-SDF-1α-CXCR4: 49.5 pM (Ki)

Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2 Preparation Products And Raw materials

Raw materials

Tag:Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2(1088715-84-7) Related Product Information

LY 294002 Hydrochloride LY-2940094 LY2828360 LY-2562175 LY2228820 Etalocib LY2584702 LY 2784544 LY2409881 trihydrochloride LY-364947 LY 88074 (S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide LY-3177833 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol LY3214996 LY2409881 LY3023414 LY2955303

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