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| | ISOPROPYLSULFONYL CHLORIDE Basic information |
| | ISOPROPYLSULFONYL CHLORIDE Chemical Properties |
| Melting point | -47°C | | Boiling point | 74-75 °C/19 mmHg (lit.) | | density | 1.27 g/mL at 25 °C (lit.) | | vapor density | 4 (vs air) | | vapor pressure | 15.5 mm Hg ( 25 °C) | | refractive index | n20/D 1.453(lit.) | | Fp | 187 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Acetontrile (Slightly), Chloroform (Slightly) | | form | clear liquid | | color | Colorless to Light yellow to Light orange | | Specific Gravity | 1.270 | | Water Solubility | Reacts with water. | | Sensitive | Lachrymatory | | BRN | 1747497 | | CAS DataBase Reference | 10147-37-2(CAS DataBase Reference) |
| | ISOPROPYLSULFONYL CHLORIDE Usage And Synthesis |
| Chemical Properties | Clear pale yellow-greenish liquid | | Uses | 2-Propanesulfonyl chloride is used as a pharmaceutical intermediate. Reductive cleavage of a secondary alcohol to methylene has been achieved by reduction of the 2-propanesulfonyl ester with lithium triethylborohydride. | | Uses | 2-Propanesulfonyl chloride (isopropylsulfonyl chloride) can be used as a reactant to prepare:
- 1-Isopropylsulfonyl-2-amine benzimidazole by reacting with 2-aminobenzimidazole via N-sulfonylation reaction in the presence of a base.
- Bis(isopropylsulfonyl)disulfide, a sulfurizing agent, used to synthesize phosphorothioate oligonucleotide analogs.
| | General Description | The solvolysis of 2-propanesulfonyl chloride by an addition-elimination (association-dissociation) pathway was studied. |
| | ISOPROPYLSULFONYL CHLORIDE Preparation Products And Raw materials |
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