| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
|
| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:Diphlorethohydroxycarmalol （DPHC）
CAS:138529-04-1
Purity:HPLC>=98% Package:20mg Remarks:B29536
|
| Company Name: |
Aktin Chemicals, Inc.
|
| Tel: |
028-85159085 |
| Email: |
info@aktinchem.com |
| Products Intro: |
Product Name:Diphlorethohydroxycarmalol （DPHC）
CAS:138529-04-1
Purity:98% Package:10mg;20mg;50mg;100mg;200mg;500mg;1g;10g;100g;可按照客户要求定制包装
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Diphlorethohydroxycarmalol
CAS:138529-04-1
Purity:95% Package:1mg;5mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Diphlorethohydroxycarmalol
CAS:138529-04-1
Package:5mg;1mg
|
|
| | Diphlorethohydroxycarmalol Basic information |
| Product Name: | Diphlorethohydroxycarmalol | | Synonyms: | Diphlorethohydroxycarmalol;Diphlorethohydroxycarmalol （DPHC）;Dibenzo[b,e][1,4]dioxin-1,2,6,8-tetrol, 7-(3,5-dihydroxyphenoxy)-3-(2,4,6-trihydroxyphenoxy)- | | CAS: | 138529-04-1 | | MF: | C24H16O13 | | MW: | 512.38 | | EINECS: | | | Product Categories: | | | Mol File: | 138529-04-1.mol |  |
| | Diphlorethohydroxycarmalol Chemical Properties |
| Boiling point | 784.9±60.0 °C(Predicted) | | density | 1.861±0.06 g/cm3(Predicted) | | pka | 6.89±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | Diphlorethohydroxycarmalol Usage And Synthesis |
| Uses | Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1]. | | in vivo | The increase of postprandial blood glucose levels are significantly suppressed in the Diphlorethohydroxycarmalol-administered group than those in the streptozotocin-induced diabetic or normal mice. Moreover, the area under curve (AUC) is significantly reduced via Diphlorethohydroxycarmalol (100 mg/kg; p.o.) administration (2022 versus 2210 mmol x min/lL) in the diabetic mice as well as it delays absorption of dietary carbohydrates[1]. | | References | [1] Soo-Jin Heo, et al. Diphlorethohydroxycarmalol isolated from Ishige okamurae, a brown algae, a potent alpha-glucosidase and alpha-amylase inhibitor, alleviates postprandial hyperglycemia in diabetic mice. Eur J Pharmacol. 2009 Aug 1;615(1-3):252-6. DOI:10.1016/j.ejphar.2009.05.017 |
| | Diphlorethohydroxycarmalol Preparation Products And Raw materials |
|