红藻氨酸
| 中文名称 | 红藻氨酸 |
|---|---|
| 中文同义词 | 红藻氨酸, **;海人草酸;卡英酸;ALPHA-红藻氨酸;紅藻胺酸;鷓鴣菜酸;(2S,3S,4S)-3-(羧基甲基)-4-(丙-1-烯-2-基)吡咯烷-2-羧酸;海藻酸(MM/ML) |
| 英文名称 | Kainic acid |
| 英文同义词 | (-)-A-KAINIC ACID;KAINIC ACID SYNTHETIC;KAINIC ACID (OPIKA-1(TM));Kainic;C12819;(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineaceticacid;3-(carboxyMethyl)-4-prop-1-en-2-ylproline;(2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic acid |
| CAS号 | 487-79-6 |
| 分子式 | C10H15NO4 |
| 分子量 | 213.23 |
| EINECS号 | |
| 相关类别 | Glutamate receptor |
| Mol文件 | 487-79-6.mol |
| 结构式 |  |
红藻氨酸 性质
| 熔点 | 253-254 C |
|---|---|
| 比旋光度 | D24 -14.8° (c = 1.01) |
| 沸点 | 353.22°C (rough estimate) |
| 密度 | 1.2177 (rough estimate) |
| 折射率 | 1.4368 (estimate) |
| 储存条件 | Keep in dark place,Sealed in dry,2-8°C |
| 溶解度 | 可溶于水中 |
| 形态 | 白色至类白色固体。 |
| 酸度系数(pKa) | 2.03±0.60(Predicted) |
| 颜色 | 白色 |
| 旋光度 (Optical Rotation) | -14.824 (H2O) |
| 水溶解性 | Soluble to 25 mM in water |
| 稳定性 | 自购买之日起 1 年内保持稳定。蒸馏水溶液可在 -20° 下保存长达 3 个月。 |
| InChI | InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1 |
| InChIKey | VLSMHEGGTFMBBZ-OOZYFLPDSA-N |
| SMILES | N1C[C@H](C(C)=C)[C@H](CC(O)=O)[C@H]1C(O)=O |
| EPA化学物质信息 | 3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S,3S,4S)- (487-79-6) |
红藻氨酸是 CNS 中兴奋性氨基酸受体亚型的有效激动剂。
Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. HO-I levels are significantly enhanced one, three and seven days after i.c.v, injection of Kainic acid. One day after i.c.v, injection of Kainic acid, the HO-I protein level reaches a maximum and then decreases, but is still significantly enhanced versus the vehicle-injected group. After i.c.v. injection of Kainic acid, HO-I-immunoreactivity is strongly induced not only in the CA3 but also widely in the whole hippocampus.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 20/21/22 |
| 安全说明 | 22-24/25-36 |
| WGK Germany | 3 |
| 存储类别 | 11 - 可燃固体 |
| 提供商 | 语言 |
|---|---|
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英文
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