| Company Name: |
BeiJing Hwrk Chemicals Limted
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| Tel: |
0757-86329057 18934348241 |
| Email: |
sales4.gd@hwrkchemical.com |
| Products Intro: |
Product Name:2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE
CAS:92505-84-5
Purity:95.00% Package:1g
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| Company Name: |
Borenpharm Co., Ltd
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| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:Amino-PEG3-alcohol HCl
CAS:92505-84-5
Purity:95% HPLC Package:1g; 5g Remarks:14g
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| | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Basic information |
| Product Name: | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE | | Synonyms: | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE;Ethanol, 2-[2-(2-aminoethoxy)ethoxy]-, hydrochloride;Amino-PEG3-alcohol HCl;NH2-PEG3 (hydrochloride);2-[(2-aminoethoxy)ethoxy]ethanol hydrochloride;HO-(CH2CH2O)3-NH2 HCl;2-(2-(2-Aminoethoxy)ethoxy)ethan-1-ol hydrochloride | | CAS: | 92505-84-5 | | MF: | C6H16ClNO3 | | MW: | 185.64914 | | EINECS: | | | Product Categories: | | | Mol File: | 92505-84-5.mol |  |
| | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Chemical Properties |
| | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Usage And Synthesis |
| Biological Activity | NH2-PEG3 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | 2-(2-(2-AMINOETHOXY)ETHOXY)ETHANOL HYDROCHLORIDE Preparation Products And Raw materials |
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