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| | BETONICINE Basic information |
| Product Name: | BETONICINE | | Synonyms: | trans-2-Carboxy-4-hydroxy-1,1-dimethylpyrrolidinium hydroxide, inner salt;(2S,4R)-4-Hydroxy-2-carboxylato-1,1-dimethylpyrrolidin-1-ium;4-Hydroxy-1,1-dimethylpyrrolidinium-2-carboxylate;4-Hydroxy-stachydrine;Aids013405;Aids-013405;Nsc655264;Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2S,4S)- | | CAS: | 515-25-3 | | MF: | C7H13NO3 | | MW: | 159.18 | | EINECS: | 208-195-6 | | Product Categories: | Alkaloids | | Mol File: | 515-25-3.mol |  |
| | BETONICINE Chemical Properties |
| Melting point | 246-248°C | | alpha | D20 -34.2° (c = 1.0) | | Boiling point | 284.67°C (rough estimate) | | density | 1.2013 (rough estimate) | | refractive index | 1.4760 (estimate) | | LogP | -4.240 (est) |
| | BETONICINE Usage And Synthesis |
| Uses | Betonicine (Achilleine), an alkaloid, has cell protectant activity. Betonicine protects Bacillus subtilis against extremes in osmolarity and growth temperatures[1]. | | Definition | ChEBI: An amino-acid betaine that is trans-4-hydroxy-L-proline zwitterion in which both of the hydrogens attached to the nitrogen have been replaced by methyl groups. | | References | [1] Bashir A, et al. Plant-derived compatible solutes proline betaine and betonicine confer enhanced osmotic and temperature stress tolerance to Bacillus subtilis. Microbiology (Reading). 2014 Oct;160(Pt 10):2283-2294. DOI:10.1099/mic.0.079665-0 |
| | BETONICINE Preparation Products And Raw materials |
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