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| 1-Methylindole-2-carboxylic acid Basic information |
| 1-Methylindole-2-carboxylic acid Chemical Properties |
Hazard Codes | Xn,Xi | Risk Statements | 22-36/37/38 | Safety Statements | 26 | WGK Germany | 3 | RTECS | NL6012400 | HazardClass | IRRITANT | HS Code | 29339980 |
| 1-Methylindole-2-carboxylic acid Usage And Synthesis |
Chemical Properties | Beige crystalline powder | Uses | - Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
- Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
- Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
- Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
- Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
- Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors
| Uses | • ;Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors1• ;Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions2• ;Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes3• ;Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation4• ;Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications ag | General Description | 1-Methylindole-2-carboxylic acid reacts with thionyl chloride to yield sulfinyl chlorides. |
| 1-Methylindole-2-carboxylic acid Preparation Products And Raw materials |
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