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Ascomycin

Ascomycin Suppliers list
Company Name: NANJING SUNSHINE BIOTECH CO.,LTD
Tel: +86-25-86189929
Email: brian@sunshine-bio.com
Products Intro: Product Name:Ascomycin
CAS:104987-12-4
Purity:98% Package:1KG;5KG;25KG;As per customer's requirement Remarks:QQ:2387265631;email:market@sunshine-bio.com
Company Name: Fuxin Pharmaceutical
Tel: 021-50872116
Email: contact@fuxinpharm.com
Products Intro: Product Name:Ascomycin
CAS:104987-12-4
Purity:99% Package:1kg; 25kg; or larger package as required
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:CBR02
CAS:104987-12-4
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Tacrolimus Impurity 5
CAS:104987-12-4
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: BOC Sciences
Tel: 1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Ascomycin (FK520)
CAS:104987-12-4
Purity:>98%

Ascomycin manufacturers

  • Ascomycin
  • $15.00-10.00 / KG
  • 2021-07-13
  • CAS:104987-12-4
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Ascomycin
  • $15.00-10.00 / KG
  • 2021-07-10
  • CAS:104987-12-4
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Ascomycin
  • $6.60 / KG
  • 2019-12-26
  • CAS:104987-12-4
  • Min. Order: 1KG
  • Purity: 97%-99%
  • Supply Ability: 1kg-1000kg
Ascomycin Basic information
Product Name:Ascomycin
Synonyms:15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetram;C058028;AscoMycin solution;L 683590, FR 900520, IMMunoMycin, FK 520, WS 7238A, NSC 106410;Ascomycin:Tacrolimus Desmethylene Impurit;Tacrolimus USP RC A;Tacrolimus Imprity 6;Ascomycin:Tacrolimus Desmethylene Impurity
CAS:104987-12-4
MF:C43 H69 N O12
MW:792.01
EINECS:600-627-5
Product Categories:antibiotic;Inhibitors;Intermediates & Fine Chemicals;Inhibits an EnzymeAntibiotics;Mechanism of Action;Spectrum of Activity;Pharmaceuticals;Macrolactams;Antibiotics;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;AntifungalAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class
Mol File:104987-12-4.mol
Ascomycin Structure
Ascomycin Chemical Properties
Melting point 153-157°C
Boiling point 868℃
density 1.19±0.1 g/cm3(Predicted)
Fp >110°(230°F)
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka9.97±0.70(Predicted)
Water Solubility Soluble in DMSO at 65mg/ml; soluble in ethanol at 50mg/m; with warming. Very poorly soluble in water
InChIKeyZDQSOHOQTUFQEM-AMASXYNMSA-N
CAS DataBase Reference104987-12-4
Safety Information
Hazard Codes Xn,F
Risk Statements 20/21/22-36-11
Safety Statements 36/37-16
RIDADR UN 1648 3 / PGII
WGK Germany 3
RTECS KD4185000
10
HS Code 29419090
MSDS Information
Ascomycin Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases
UsesAscomycin is a macrocyclic lactone closely related to tacrolimus and rapamycin. Ascomycin is isolated from several species of Streptomyces and was first reported in 1988. Ascomycin exhibits limited, potent antifungal activity but has found considerable utility as an immunosuppressant.
UsesEverolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a silyl-protected hydroxyethyl triflate moiety, followed by addition of an ethylhydroxy moiety to provide greater stability and bioavailability. Like all tacrolimus analogues, everolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Everolimus is extensively cited in the literature with over 2,000 citations.
DefinitionChEBI: A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties.
Ascomycin Preparation Products And Raw materials
Tag:Ascomycin(104987-12-4) Related Product Information
Spiramycin 19-Epi FK-506 8-EpitacroliMus Tacrolimus Hydroxy Acid Impurity Δ23-FK-506 (E/Z)-FK-506 26,28-Allylic Ester RearrangeMent IMpurity Iso-FK-506 (iso-TacroliMus) TacroliMus Methyl Acryl Aldehyde Tacrolimus Open Ring Impurity Tacrolimus Ring-opening Impurity Dihydro-FK506 AAG PROTEIN,MOUSE AAG 5'-TAT TAG GAC AAG GCT GGT GGG CAC-3' 17-AAG (17-(Allylamino)-17-demethoxygeldanamycin), Geldanamycin derivative, 0.5857kD 32-O-(1-hydroxyethylindol-5-yl)ascomycin 17-AAG 17AAG-d5 AAG, MPG,AAG