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Rebeprazole sodium

Rebeprazole sodium Suppliers list
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Products Intro: Product Name:Rebeprazole sodium
Purity:99% Package:6050/KG
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Rebeprazole sodium
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:117976-90-6
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: PI & PI BIOTECH INC.
Tel: 020-81716320
Products Intro: Product Name:Rabeprazole Sodium
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Remarks:Sodium 2-[(RS)-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]benzimidazol-1-ide
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366
Products Intro: Product Name:Rebeprazole sodium
Purity:99% Package:100g;500g;1kg;25kg...

Lastest Price from Rebeprazole sodium manufacturers

  • Rebeprazole sodium
  • US $1.00 / kg
  • 2018-12-17
  • CAS:117976-90-6
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: Customized
Rebeprazole sodium Basic information
Anti-ulcer drug Uses
Product Name:Rebeprazole sodium
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;-;Rabeprazole
Mol File:117976-90-6.mol
Rebeprazole sodium Structure
Rebeprazole sodium Chemical Properties
Melting point 140-141°C dec.
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility H2O: soluble10mg/mL (clear solution)
form powder
color white to beige
Merck 14,8089
Safety Information
WGK Germany 3
MSDS Information
Rebeprazole sodium Usage And Synthesis
Anti-ulcer drugRabeprazole sodium is a anti-ulcer disease drug belonging to proton pump inhibitor and is the sodium salt form of Rabeprazole. The Japanese company Eisai had successfully developed it for the first time with the trade name being “Bolite”. The function of the proton pump inhibitors is reducing the gastric acid secretion so that the lesion site can be stable in order to achieving the effect of curing gastric and duodenal ulcers and stomach-esophageal reflux disease. Clinically it is majorly used for the treatment of acid-related diseases such as stomach and duodenal ulcers, peptic ulcer, gastroesophageal reflux disease and zollinger-ellison syndrome. Rabeprazole is a kind of benzimidazole-substituted compounds. It inhibits the secretion of gastric acid through forming bond with the cytoplasmic proton pump in the gastric cavity wall. This product can specifically inhibit the effect of the adenosine triphosphatase that is the key enzyme during the production of stomach acid. It has inhibitory effect on both basal gastric acid and the gastric acid secretion caused by the stimulation.
Rabeprazole is white-yellowish-white powder with no odor and a molecular weight being 381.43. This product is highly soluble in water or methanol, also soluble in ethanol or ethyl acetate but almost insoluble in ether or ethane. This product does not exhibit optical activity, has hygroscopic effect. Its melting point is 225 ℃ and its partition coefficient at water/octane system of pH 7.0 is about 214. This product is light yellow film-coated tablets (enteric-coated tablets).
Adverse reactions and precautions: gastric cancer should be excluded after use of the drug. Adverse reactions include allergic reactions, palpitations, constipation, diarrhea, headache, edema, leukopenia, AST, ALT, total bilirubin and proteinuria. The combination of Rabeprazole sodium and digoxin can cause increased digoxin concentration. It can’t be taken simultaneously with antacids. Patients of history of drug allergy, cirrhosis, the elderly, pregnant and lactating women, children should take with caution.
The above information is edited by the chemicalbook of Dai Xiongfeng.
UsesIt belongs to national second-class drug that can be used for the treatment of gastric ulcer. It can be used for the treatment of peptic ulcer, gastroesophageal reflux disease, zollinger-ellison syndrome and other diseases.
Chemical PropertiesWhite Crystalline Solid
Usesanthelminthic, antiseptic, expectorant
Usesantibacterial and antifungal agent effective against gram-positive and gram-negative bacteria, yeast and fungi
UsesA partially reversible gastric proton pump inhibitor
Brand nameAciphex (Eisai Medical Research) .
Rebeprazole sodium Preparation Products And Raw materials
Tag:Rebeprazole sodium(117976-90-6) Related Product Information
Rabeprazole intermediates 2-Hydroxymethyl-3-methyl-4-(3-methoxy propanoxyl)pyridine 2-Hydroxybenzimidazole 4-Nitro-2,3-lutidine-N-oxide (S)-Rabeprazole Sodium Salt Pantoprazole Omeprazole Rabeprazole IMIDAZOLE SODIUM DERIVATIVE 2-[(4-METHOXY-3-METHYL-2-PYRIDINYL)-METHYLTHIO]-BENZIMIDAZOLE Rebeprazole sodium 1-Propanol, 3-[[2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-3-methyl-4-pyridinyl]oxy]- Pyridine Sodium Rabeprazole Enteric-coated Tablet Timoprazole 2-{[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl]methylthio}-1H-benzimidazole 2-[(4-ETHOXY-3-METHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE