1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine

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Products Intro: Product Name:1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE)
CAS:4004-05-1
Purity:98% Package:1g;USD|10g;USD|100g;USD
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Products Intro: Product Name:dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE)
CAS:4004-05-1
Purity:98% Package:1g;USD|10g;USD|100g;USD|1KG;USD
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Products Intro: Product Name:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
CAS:4004-05-1
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Products Intro: Product Name:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
CAS:4004-05-1
Purity:99%+ HPLC Package:1KG;15USD|100KG;12USD|1000KG;10USD

1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine manufacturers

1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Basic information
Product Name:1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine
Synonyms:3-SN-PHOSPHATIDYLETHANOLAMINE, 1,2-DIDEOYL;1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;1,2-DI([CIS]-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHOETHANOLAMINE;18:1 PE;L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL;L-ALPHA-PHOSPHATIDYLETHANOLAMINE, DIOLEOYL (C18:1,[CIS]-9);L-BETA,GAMMA-DIOLEOYL-ALPHA-CEPHALIN;DIOLEOYL PHOSPHATIDYL ETHANOLAMINE
CAS:4004-05-1
MF:C41H78NO8P
MW:744.05
EINECS:200-663-8
Product Categories:
Mol File:4004-05-1.mol
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Structure
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Chemical Properties
Melting point 200°C(lit.)
Boiling point 759.2±70.0 °C(Predicted)
density 1.008±0.06 g/cm3(Predicted)
storage temp. -20°C
form lyophilized powder
pka1.17±0.50(Predicted)
BRN 1718431
Safety Information
Hazard Codes Xn
Risk Statements 22-38-40-48/20/22-67-36/38-20-63
Safety Statements 36/37-26
RIDADR UN 1888 6.1/PG 3
WGK Germany 3
8-10-23
HS Code 29232000
MSDS Information
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SigmaAldrich English
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Usage And Synthesis
Description1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) is a neutral phospholipid and displays sensitivity towards pH change and has been used in the preparation of liposome and giant unilamellar vesicles (GUVs).
Phosphatidylethanolamine (PE) is formed primarily in the reaction of CDP-ethanolamine and diacylglycerol. PE is one of the major components of cell membranes in bacteria and in nervous system.
Chemical PropertiesYellowish wax
Uses1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents.
Uses1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
Application1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
DefinitionChEBI: Dioleoyl phosphatidylethanolamine is a phosphatidylethanolamine in which the phosphatidyl acyl groups are both oleoyl.
Biological ActivityDOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).
Biochem/physiol ActionsDOPE in mixed membranes have been found to decrease fluorescence lifetime and increase acyl-chain order. DOPE is an essential component of cationic liposomes designed to deliver DNA into gliosarcoma and kidney cell lines (gene therapy).
1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine Preparation Products And Raw materials
Tag:1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine(4004-05-1) Related Product Information
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(SUCCINYL) 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(GLUTARYL) 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL) 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(CARBOXYFLUORESCEIN) 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(BIOTINYL) N-(NBD-AMINOHEXANOYL)-1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE SODIUM SALT N-(NBD)-AMINODODECANOYL-1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE SODIUM SALT 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[3-(2-PYRIDYLDITHIO)PROPIONATE] 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-METHYL 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[4-(P-MALEIMIDOMETHYL)CYCLOHEXANE-CARBOXYLATE] DOPS L-3-PHOSPHATIDYL-L-[3-14C]SERINE,1,2-DIOLEOYL 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamino caproylmaleimide 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, FLUORESCEIN-LABELED,N-(FLUORESCEIN-5-CARBONYL)-1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE L-3-PHOSPHATIDYL[2-14C]ETHANOLAMINE,1,2-DIOLEOYL 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHATIDYLETHANOLAMINE 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamino (+)-biotin