BAY-545 manufacturers
- BAY-545
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- $81.00 / 1mg
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2025-04-27
- CAS:1699717-32-2
- Min. Order:
- Purity: 98.05%
- Supply Ability: 10g
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| | BAY-545 Basic information |
| Product Name: | BAY-545 | | Synonyms: | BAY-545;BAY-545;BAY545;BAY 545;1699717-32-2;Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-;3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit;BAY-545, 10 mM in DMSO | | CAS: | 1699717-32-2 | | MF: | C18H22F3N3O4S | | MW: | 433.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1699717-32-2.mol |  |
| | BAY-545 Chemical Properties |
| Boiling point | 598.7±60.0 °C(Predicted) | | density | 1.410±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:129.0(Max Conc. mg/mL);297.61(Max Conc. mM)
Ethanol:87.0(Max Conc. mg/mL);200.72(Max Conc. mM) | | form | A solid | | pka | 14.56±0.20(Predicted) | | color | White to off-white |
| | BAY-545 Usage And Synthesis |
| Uses | BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor[1]. | | References | [1] H?rter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem. 2019 Feb 1;163:763-778. DOI:10.1016/j.ejmech.2018.11.045 |
| | BAY-545 Preparation Products And Raw materials |
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