I-191
(I191) manufacturers
- I-191
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- $82.00 / 1mg
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2025-04-28
- CAS:1690172-25-8
- Min. Order:
- Purity: 99.80%
- Supply Ability: 10g
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| | I-191
(I191) Basic information |
| Product Name: | I-191
(I191) | | Synonyms: | I-191
(I191);I-191;2-Piperazinone, 4-[[8-(1,1-dimethylethyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]carbonyl]-3,3-dimethyl-;4-(8-(tert-Butyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl)-3,3-dimethylpiperazin-2-one;I-191,Inhibitor,I191,inhibit,I 191,Protease Activated Receptor (PAR),Thrombin receptors;4-(8-(tert-Butyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl)-3,3-dimethylpiperazin-2-one , I-191;I-191, 10 mM in DMSO | | CAS: | 1690172-25-8 | | MF: | C23H26FN5O2 | | MW: | 423.48 | | EINECS: | | | Product Categories: | | | Mol File: | 1690172-25-8.mol |  |
| | I-191
(I191) Chemical Properties |
| density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 8.33 mg/mL (19.67 mM; Need ultrasonic)| | | pka | 13.69±0.40(Predicted) | | form | Solid | | color | White to gray | | Water Solubility | Water : < 0.1 mg/mL (insoluble) |
| | I-191
(I191) Usage And Synthesis |
| Uses | I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist[1]. | | IC 50 | PAR2 | | References | [1] Jiang Y, et al. A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells. J Pharmacol Exp Ther. 2018 Feb;364(2):246-257. DOI:10.1124/jpet.117.245027 |
| | I-191
(I191) Preparation Products And Raw materials |
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