LIN28 inhibitor LI71 manufacturers
- LIN28 inhibitor LI71
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- $139.00 / 1mg
-
2025-04-28
- CAS:1357248-83-9
- Min. Order:
- Purity: 95.88%
- Supply Ability: 10g
- LIN28 inhibitor LI71
-
- $139.00 / 1mg
-
2025-04-27
- CAS:1357248-83-9
- Min. Order:
- Purity: 95.88%
- Supply Ability: 10g
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| | LIN28 inhibitor LI71 Basic information |
| Product Name: | LIN28 inhibitor LI71 | | Synonyms: | 4-((3aS,4R,9bR)-6-Ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid;LIN28 inhibitor LI71;Benzoic acid, 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-;LIN28 inhibitor LI72;LIN28 inhibitor LI71,MicroRNA,LIN-28 inhibitor LI71,inhibit,Inhibitor,miRNA;LIN28 inhibitor LI71, 10 mM in DMSO | | CAS: | 1357248-83-9 | | MF: | C21H21NO3 | | MW: | 335.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1357248-83-9.mol |  |
| | LIN28 inhibitor LI71 Chemical Properties |
| storage temp. | 2-8°C(protect from light) | | solubility | DMSO:100.0(Max Conc. mg/mL);298.15(Max Conc. mM) | | form | Solid | | color | Yellow to green |
| | LIN28 inhibitor LI71 Usage And Synthesis |
| Uses | LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells[1]. | | References | [1] Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018 Jun 5;23(10):3091-3101. DOI:10.1016/j.celrep.2018.04.116 |
| | LIN28 inhibitor LI71 Preparation Products And Raw materials |
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