| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-85563444 18351873721 |
| Email: |
purchase@synzest.com |
| Products Intro: |
Product Name:TCO-PEG8-acid
CAS:2353410-03-2
Purity:95%HPLC Package:50mg;100mg;250mg;1g
|
| Company Name: |
Zhengzhou Akem Chemical Co., Ltd
|
| Tel: |
13303867194 |
| Email: |
3001317055@qq.com |
| Products Intro: |
Product Name:TCO-PEG8-acid
CAS:2353410-03-2
Purity:95% Package:100mg；250mg；1g；
|
|
| | TCO-PEG8-acid Basic information |
| Product Name: | TCO-PEG8-acid | | Synonyms: | TCO-PEG8-acid;5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(4-cycloocten-1-yl) ester | | CAS: | 2353410-03-2 | | MF: | C28H51NO12 | | MW: | 593.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2353410-03-2.mol |  |
| | TCO-PEG8-acid Chemical Properties |
| Boiling point | 686.5±55.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | solubility | Soluble in Water, DMSO, DCM, DMF | | pka | 4.28±0.10(Predicted) |
| | TCO-PEG8-acid Usage And Synthesis |
| Description | TCO-PEG8-acid is a very reactive click chemistry reagent. The terminal carboxylic acid (CO2H) can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable bond. TCO moiety is reactive with tetrazine-containing compounds to form a stable bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The hydrophilic PEG spacer increases solubility in aqueous media. |
| | TCO-PEG8-acid Preparation Products And Raw materials |
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