膦胺霉素
| 中文名称 | 膦胺霉素 |
|---|---|
| 中文同义词 | 膦胺霉素;膦胺霉素钠盐;磷霉素钠盐;化合物 T11315;抗生素 FR-31564 |
| 英文名称 | FOSMIDOMYCIN, SODIUM SALT |
| 英文同义词 | 3-(N-FORMYL-N-HYDROXYAMINO)PROPYL PHOSPHONIC ACID, SODIUM SALT;(3-(formylhydroxyamino)propyl)phosphonicacidmonosodiumsalt;(3-(formylhydroxyamino)propyl)-phosphonicacimonosodiumsalt;antibioticfr31564;fosmidomycin;Fosmidomycinesodiumsalt;3-(N-Formyl-N-hydroxyamino)propyl Phosphonic Acid, Sodium Salt, FR31564;FR31564 |
| CAS号 | 66508-37-0 |
| 分子式 | C4H11NNaO5P |
| 分子量 | 207.1 |
| EINECS号 | |
| 相关类别 | 对照品;Inhibitors;Aliphatics;Intermediates & Fine Chemicals;Pharmaceuticals;All Inhibitors;Phosphorylating and Phosphitylating Agents |
| Mol文件 | 66508-37-0.mol |
| 结构式 |  |
膦胺霉素 性质
| 熔点 | 189-191°C |
|---|---|
| 储存条件 | -20°C Freezer |
| 溶解度 | DMSO（轻微）、甲醇（轻微、加热）、水（轻微） |
| 形态 | 固体 |
| 颜色 | 白色至米色 |
| 稳定性 | 吸湿性 |
Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾药，对革兰氏阴性菌和革兰氏阳性菌均有活性。
Fosmidomycin sodium salt is a phosphonic acid antibiotic, which is active against both Gram-negative and Gram-positive bacteria.
Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured.
安全信息
| 危险品标志 | C |
|---|---|
| 危险类别码 | 34 |
| 安全说明 | 26-27-36/37/39-45 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-112853 | 膦胺霉素 Fosmidomycin sodium salt | 66508-37-0 | 5 mg | 1400元 |
| 2024/01/25 | HY-112853 | 膦胺霉素 Fosmidomycin sodium salt | 66508-37-0 | 10 mM * 1 mLin Water | 1540元 |