Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
Products Intro: |
Product Name:Ribavirin 5'-Monophosphate DilithiuM Salt (90%) CAS:66983-94-6 Package:50Mg,5Mg
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| RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Basic information |
| RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Chemical Properties |
Melting point | 220°C dec. | storage temp. | -20°C Freezer | solubility | Aqueous Acid (Slightly), Water (Slightly, Sonicated) | form | Solid | color | Off-White to Pale Beige | Stability: | Hygroscopic |
| RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Usage And Synthesis |
Description | Ribavirin 5''-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH), with a reported Ki value of 270 nM, and thus inhibits guanosine triphosphate synthesis. This agent, a metabolite of the prodrug ribavirin , exhibits broad-spectrum antiviral activity, particularly against myxoviruses. The antiviral effects of ribavirin require conversion to the monophosphate form via adenosine kinase. The anti-HIV activity of ribavirin in cultured human lymphocytes, as well as the anti-influenza activity of this prodrug in MDCK cells, have been attributed to ribavirin 5''-monophosphate. | Chemical Properties | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is Solid | Uses | A metabolite of Ribavirin. | Uses | RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT is used as an antiviral agent |
| RIBAVIRIN 5'-MONOPHOSPHATE, DILITHIUM SALT Preparation Products And Raw materials |
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