| Company Name: |
BOC Sciences
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16314854226 |
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Product Name:SR 1903
CAS:1414248-06-8
Purity:98% Package:1G;10G;100G Remarks:SR 1903 is an inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and an agonist of liver X receptor (LXR). It also binds to PPARγ without activity. It reduces blood glucose lev
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:SR 1903
CAS:1414248-06-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
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4008200310 |
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marketing@tsbiochem.com |
| Products Intro: |
Product Name:SR 1903;SR 1903
CAS:1414248-06-8
Purity:98% Package:50 mg
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| Company Name: |
Nanjing Tengyi Biotechnology Co., Ltd
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025-58851786 17714337195 |
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Product Name:2'-methyl-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol
CAS:1414248-06-8
Purity:95+% Package:1g;5g
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| | SR 1903 Basic information |
| Product Name: | SR 1903 | | Synonyms: | SR 1903;[1,1'-Biphenyl]-4-methanol, 2'-methyl-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-;2'-methyl-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol | | CAS: | 1414248-06-8 | | MF: | C27H27F6N3O | | MW: | 523.52 | | EINECS: | | | Product Categories: | | | Mol File: | 1414248-06-8.mol |  |
| | SR 1903 Chemical Properties |
| Boiling point | 559.0±50.0 °C(Predicted) | | density | 1.307±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml | | form | A crystalline solid | | pka | 9.23±0.15(Predicted) |
| | SR 1903 Usage And Synthesis |
| Description | SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1). It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity. |
| | SR 1903 Preparation Products And Raw materials |
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