ChemicalBook > Product Catalog >Biochemical Engineering >Biochemical Reagents >2-Thiothymidine

2-Thiothymidine

2-Thiothymidine Suppliers list
Company Name: PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD
Tel: 0371-55159968 18137130222
Email: haifeng.zhang@pannacean.com
Products Intro: Product Name:2-THIOTHYMIDINE
CAS:28585-51-5
Purity:0.97 Package:5g;10;15;1kg
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:2-Thiothymidine
CAS:28585-51-5
Purity:>=95% by HPLC Remarks:BOC Sciences also provides custom synthesis services for 2-Thiothymidine.
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:2-thio-2'-deoxythymidine
CAS:28585-51-5
Purity:0.99 Package:1kg
Company Name: SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Products Intro: Product Name:2-Thiothymidine
CAS:28585-51-5
Purity:98% Package:Package as requetsed
Company Name: Hefei Hirisun Pharmatech Co., Ltd
Tel: +8615056975894
Email: shawn@hirisunpharm.com
Products Intro: Product Name:2-Thiothymidine
CAS:28585-51-5
Purity:0.95 Package:1G;5G;25G;Bulk for inquiry Remarks:HR040011
2-Thiothymidine Basic information
Product Name:2-Thiothymidine
Synonyms:2-THIOTHYMIDINE;1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one;2-Thio-2'-deoxythymidine;2'-deoxy-5-methyl-2-thiouridine;1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;Thymidine, 2-thio-;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS:28585-51-5
MF:C10H14N2O4S
MW:258.29
EINECS:
Product Categories:
Mol File:28585-51-5.mol
2-Thiothymidine Structure
2-Thiothymidine Chemical Properties
InChIInChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKeyPISWNSOQFZRVJK-XLPZGREQSA-N
SMILESOC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O
Safety Information
MSDS Information
2-Thiothymidine Usage And Synthesis
Uses2-Thiothymidine is a mRNA therapy used for treatment of ornithine transcarbamylase deficiency.
Application2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.
Definition 2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc
2-Thiothymidine Preparation Products And Raw materials
Tag:2-Thiothymidine(28585-51-5) Related Product Information
Nucleoside 1-(2-HYDROXY-ETHOXYMETHYL)-2-THIOXO-2,3-DIHYDRO-1H-PYRIMIDIN-4-ONE 5-METHYL-2-THIOURIDINE 2-THIOTHYMIDINE-5'-TRIPHOSPHATE LITHIUM SALT 2-Thiothymidine