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Hypericin

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Company Name: Chengdu Biopurify Phytochemicals Ltd.
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Products Intro: Product Name:Hypericin
CAS:548-04-9
Purity:90%~98% HPLC Package:20mg;100mg;500mg;1g Remarks:BP0752
Company Name: Henan Tianfu Chemical Co.,Ltd.
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CAS:548-04-9
Purity:As coa Package:As request Remarks:548-04-9
Company Name: Shanghai Zheyan Biotech Co., Ltd.
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Products Intro: Product Name:Hypericin
CAS:548-04-9
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Products Intro: Product Name:Hypericin
CAS:548-04-9
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Hypericin manufacturers

  • Hypericin 548-04-9
  • $650.00 / g
  • 2021-11-17
  • CAS:548-04-9
  • Min. Order: 10mg
  • Purity: ≥98%
  • Supply Ability: 1000.00 kgs
  • Hypericin
  • $130.00 / ml
  • 2021-11-02
  • CAS:548-04-9
  • Min. Order: 10ml
  • Purity: 99%
  • Supply Ability: 1kg
  • Hypericin
  • $1218.00 / g
  • 2021-07-30
  • CAS:548-04-9
  • Min. Order: 1g
  • Purity: 98%
  • Supply Ability: 1kg

Related articles

  • Application of Hypericin
  • Hypericin is a naturally occurring substance found in the common St. John's Wort (Hypericum species) and can also be synthesiz....
  • Sep 19,2019
Hypericin Basic information
Hypericum perforatum extracts Indications Uses
Product Name:Hypericin
Synonyms:HYPERICUM RED;HYPERICIN;HYPERICIN (NATIVE);CYCLOSAN;CYCLO-WERROL;1,3,4,6,8,13-HEXAHYDROXY-10,11-DIMETHYLPHENANTHRO[1,10,9,8-OPQRA]PERYLENE-7,14-DIONE;1,3,4,6,8,13-HEXAHYDROXY-10,11-DIMETHYLPHENANTHROL(1,10,9,8,OPQRA)PERYLENE-7,14-DIONE;MYCOPOPHYRIN
CAS:548-04-9
MF:C30H16O8
MW:504.44
EINECS:208-941-0
Product Categories:Nutraceuticals;Antitumour;Anthraquinones, Hydroquinones and Quinones;Natural Plant Extract;chemical reagent;antibiotic;plant extract;Plant extracts;Herb extract;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:548-04-9.mol
Hypericin Structure
Hypericin Chemical Properties
Melting point 299-301°C
Boiling point 1020.3±65.0 °C(Predicted)
density 1.915±0.06 g/cm3(Predicted)
RTECS SF8472000
storage temp. -20°C
solubility 1 M NaOH: 10 mg/mL
form powder
pka6.91±0.20(Predicted)
color black
Water Solubility Soluble in ethanol, dimethyl sulfoxide, methanol, acetone, ethylmethylketone, pyridine and sodium hydroxide. Insoluble in water.
Sensitive Light Sensitive
Merck 14,4863
BRN 1917913
InChIKeyBTXNYTINYBABQR-UHFFFAOYSA-N
CAS DataBase Reference548-04-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22-40-43
Safety Statements 22-36-36/37
RIDADR 2811
WGK Germany 3
8
HS Code 29145090
MSDS Information
ProviderLanguage
SigmaAldrich English
Hypericin Usage And Synthesis
Hypericum perforatum extractsHypericin is an extract of Hypericum perforatum L.In 1957. It is first isolated from the Garcinia species Hypericum perforatum by human beings. Hypericin belongs to the bianthrone compounds, and it is the most biologically active substances. Hypericin is a yellowish brown to brown mobile powder, with slightly bitter taste. It is soluble in water, and can emit a special fragrance. It can inhibit the central nervous and has a sedative effect. Adding it to health care products can enhance immunity. It is also used as antidepressant drugs in Europe (especially in Germany). Hypericin also has a strong anti-viral effect, which can directly act on swine fever, foot and mouth disease and other viruses. In addition, it also has a good effect on killing highly pathogenic avian influenza virus.
Hypericum perforatum is one of the world's best-selling herbs in recent years, mainly containing hyperoside, quercetin, chlorogenic acid, caffeic acid, imanin, hypericin and other ingredients.
Hypericin is a few thousandths of the whole Hypericum perforatum. There are certain requirements for its extraction and testing. Methanol extraction method is common used in the past. Due to the toxicity of methanol, now the method is   converted to use ethanol to obtain the active ingredient.
IndicationsHypericin is an anti-virus and pure Chinese medicine preparations. It is the first choice for the prevention and treatment of avian influenza drugs.
1, avian influenza, atypical Newcastle disease, infectious bronchitis, avian infectious laryngotracheitis , bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases.
2, poultry fever caused by high fever, dyspnea, cough, head and face swelling, crown hair purple, lack of energy, decreased feed intake, egg drop, producing more abnormal eggs.
3, for classical swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction.
4, Hypericin has a strong anti-viral effect both in vivo and in vitro. It has a strong inhibitory effect on the early replication of HIV. Hypericin can lead to cancer cell programmed death, with anti-cancer effect. It has a enhanced immune function  for activating mononuclear phagocytic cells. In addition, it has a strong role in killing the highly pathogenic H5N1 and H9N2 subtype of avian influenza virus.
Uses(1) Antidepressant, increase immunity.
(2) For the treatment of antidepressants, increase immunity.
DescriptionAn anthroquinone derivative that is naturally found in the flower of H. perforatum (St. John’s wort) and has antidepressant, antiviral, and anticancer activities. Hypericin inhibits neuronal uptake of serotonin, norepinephrine, dopamine, GABA and L-glutamate, contributing to its antidepressant effects. It exerts broad spectrum phototoxic affects (IC50 = 140 - 1,570 nM) through induction of apoptotic signaling and formation of reactive oxygen species (ROS) in cancer cells. Hypericin also has in vitro activity, which can be enhanced with photo-activation, against a variety of viruses including HIV, influenza virus, hepatitis C, murine cytolomegalovirus, and herpes viruses.
Chemical PropertiesPowder
Uses
It was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.
General Description
Produced by HWI Analytik
Exact content can be found on the certificate
Biological ActivityPhotosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort). Inactivates enveloped viruses (including HIV), inhibits tyrosine kinases (IC 50 = 7.5 μ M) and is preferentially cytotoxic to tumor cells upon stimulation by visible light.
Biochem/physiol ActionsPrimary TargetPKC
Purification MethodsCrystallise hypericin from pyridine by addition of methanolic HCl. [Beilstein 8 IV 3761.]
Hypericin Preparation Products And Raw materials
Tag:Hypericin(548-04-9) Related Product Information
TOTAL DIANTHRONES((CALC. AS HYPERICIN) UV Tosylmethyl isocyanide Cupric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) HYPERICIN SODIUM SALT Tris(2,4-pentanedionato)chroMiuM(III) COBALT ETHYLENE DIAMINE CHLORIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE Ferric acetylacetonate 2,4-PENTANEDIONE, SILVER DERIVATIVE N-BUTYLISOCYANIDE Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) COBALT(II) ACETYLACETONATE Hypericin