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Citalopram hydrobromide

Citalopram hydrobromide (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant agents. Citalopram HBr occurs as a fine, white to off-white powder. Citalopram HBr is sparingly soluble in water and soluble in ethanol. The tablet is available as the brand-name drug Celexa. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.
Citalopram hydrobromide Suppliers list
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Products Intro: Product Name:Citalopram hydrobromide
CAS:59729-32-7
Purity:99% Package:1760/KG
Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:Citalopram hydrobromide
CAS:59729-32-7
Purity:99% Package:100g,500g,1KG,10KG,100KG
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Products Intro: Product Name:Citalopram hydrobromide
CAS:59729-32-7
Purity:98% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: CAS:59729-32-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Citalopram hydrobromide
CAS:59729-32-7
Citalopram hydrobromide Basic information
Abstract Efficacy Side effects References
Product Name:Citalopram hydrobromide
Synonyms:1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobromi;Citalopram hydrobromide solution;Citalopram HBr Salt;1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrobr;1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBONITRILE HYDROBROMIDE;5-ISOBENZOFURANCARBONITRILE, 1,3-DIHYDRO-1-(3-(DIMETHYLAMINO)PROPYL)-1-(4-FLUOROPHENYL)-;CITALOPRAM HBR;(+/-)-CITALOPRAM HYDROBROMIDE
CAS:59729-32-7
MF:C20H22BrFN2O
MW:405.3
EINECS:261-890-6
Product Categories:Other APIs;Heterocyclic Compounds;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Citalopram;Serotonin;APIs;Neurochemicals,Pharmaceuticals;Pharmaceutical intermdiate
Mol File:59729-32-7.mol
Citalopram hydrobromide Structure
Citalopram hydrobromide Chemical Properties
Melting point 182-188°C
Fp 9℃
storage temp. -20°C Freezer
solubility H2O: soluble (sparingly)
Merck 14,2318
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference59729-32-7(CAS DataBase Reference)
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25-22
Safety Statements 7-16-36/37-45-24/25
RIDADR 3249
RTECS NP6313500
HazardClass 6.1(b)
PackingGroup III
HS Code 29329990
Hazardous Substances Data59729-32-7(Hazardous Substances Data)
MSDS Information
Citalopram hydrobromide Usage And Synthesis
AbstractCitalopram hydrobromide (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant agents.
Citalopram HBr occurs as a fine, white to off-white powder. Citalopram HBr is sparingly soluble in water and soluble in ethanol.
The tablet is available as the brand-name drug Celexa. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.
EfficacyThe advantage of this drug is that it has no effect on cholinergic muscarinic receptors, histamine receptors and α-adrenergic receptors . Because if these receptors are inhibited,  a lot of side effects caused by antidepressants will produce, such as dry mouth, sedation, orthostatic hypotension. Citalopram hydrobromide is effective for not only endogenous depression patients but also non-endogenous depression patients. Its antidepressant effect is usually established after 2-4 weeks . Citalopram hydrobromide does not affect the cardiac conduction system and blood pressure, which is particularly important for elderly patients. In addition, citalopram hydrobromide does not affect the blood, liver and kidney systems. Rare side effects and the most mild sedative properties make it particularly suitable for long-term treatment.It does not lead to weight gaining,and it does not strengthen the role of alcohol.
Side effectsYou should not use this medicine if you are allergic to citalopram or escitalopram (Lexapro), or if you also take pimozide.
Do not use citalopram if you have used an monoamine oxidase inhibitor (MAOI) in the past 14 days. A dangerous drug interaction could occur. MAOI inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Side effects are usually small, very mild and transient. The most common adverse reactions are: nausea, increased sweating, salivation reduction, headaches and sleep time shortening. They are usually more obvious in the first or second week when treatment begins, and they generally disappear with the improvement of depression. In rare cases ,seizures have been observed. For  patients who suffer bradycardia , bradycardia can make treatment more complicated.
Referenceshttp://www.rxlist.com/celexa-drug.htm
https://en.wikipedia.org/wiki/Citalopram
https://www.drugs.com/citalopram.html
Chemical PropertiesWhite Crystalline Powder
UsesAntidepressant;5HT uptake inhibitor
UsesAnti-depressant/Anti-psychotic
UsesAn inhibitor of serotonin (5-HT) uptake. Used as an antidepressant
Brand nameCelexa (Forest).
Citalopram hydrobromide Preparation Products And Raw materials
Tag:Citalopram hydrobromide(59729-32-7) Related Product Information
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