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3-METHOXYCATECHOL

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  • 3-Methoxycatechol
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  • $29.00 / 1g
  • 2025-11-07
  • CAS:934-00-9
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  • Purity: 99.31%
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  • 2025-09-25
  • CAS:934-00-9
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  • 3-Methoxycatechol
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3-METHOXYCATECHOL Basic information
Product Name:3-METHOXYCATECHOL
Synonyms:1,2-Dihydroxy-3-methoxybenzene, 3-Methoxypyrocatechol, Pyrogallol monomethyl ether;3-Methoxycatechol,99%;3-Methoxycatechol,1,2-Dihydroxy-3-methoxybenzene, 3-Methoxypyrocatechol, Pyrogallol monomethyl ether;1-O-Methylpyrogallol;2-Hydroxy-3-methoxyphenol;3-Methoxy-1,2-dihydroxybenzene;3-Methoxy-o-hydroquinone;NSC 66525
CAS:934-00-9
MF:C7H8O3
MW:140.14
EINECS:213-276-4
Product Categories:Aromatic Ethers;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Polyols
Mol File:934-00-9.mol
3-METHOXYCATECHOL Structure
3-METHOXYCATECHOL Chemical Properties
Melting point 38-43 °C (lit.)
Boiling point 146-147 °C/15 mmHg (lit.)
density 1.270
refractive index 1.4638 (estimate)
Fp >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka9.42±0.10(Predicted)
color White to Off-White
BRN 1909165
InChIInChI=1S/C7H8O3/c1-10-6-4-2-3-5(8)7(6)9/h2-4,8-9H,1H3
InChIKeyLPYUENQFPVNPHY-UHFFFAOYSA-N
SMILESC1(O)=CC=CC(OC)=C1O
LogP0.937 (est)
CAS DataBase Reference934-00-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS CZ9002750
HS Code 29095000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
3-METHOXYCATECHOL Usage And Synthesis
Chemical PropertiesSLIGHTLY BEIGE TO LIGHT BROWN CRYSTALLINE SOLID
Uses3-Methoxycatechol is used to prepare polyphenolic deoxybenzoins as potential antioxidants and tyrosinase inhibitors.
DefinitionChEBI: 3-methoxycatechol is a member of the class of catechols that is catechol in which a hydrogen that is ortho to one of the hydroxy groups has been replaced by a methoxy group. It displays agonistic activity against G protein-coupled receptor 35 (GPR35). It has a role as a G-protein-coupled receptor agonist. It is a member of catechols and an aromatic ether. It is functionally related to a pyrogallol.
Synthesis2,3-Dihydroxyanisole is synthesised using 2-hydroxy-3-methoxybenzaldehyde as a raw material by chemical reaction. The specific synthesis steps are as follows:
To a solution of 2-hydroxy-3-methoxybenzaldehyde (o-vanillin) (20.3 g,0.134 mole)in aqueous sodium hydroxide (2N,66.6 ml,0.133 mole)is added dropwise hydrogen peroxide (6%,95 ml,0.167 mole) during 1 hr at 40-45(the solution is cooled if necessary).After the reaction is over,the reaction mixture is allowed to cool to room temperature.It is saturated with sodium chloride and then extracted with ether (3 x 70 ml).The ether solution is dried (sodium sulphate)and distilled.The residual product is distilled and the fraction boiling at 136-38/22 mm is collected.Yield 11 g (58.8%)(lit.b.p.136-38/22 mm).
2,3-Dihydroxyanisole synthesis
Tag:3-METHOXYCATECHOL(934-00-9) Related Product Information
7,8-Dihydroxyflavone 2,3,4-TRIMETHOXYBENZYL ALCOHOL PYROGALLOL RED 3,4,5-Trimethoxybenzyl alcohol 3,4,5-Trimethoxybenzaldehyde 3,4,5-Trimethoxy benzoic acid 4-Hydroxy-3,5-dimethoxycinnamic acid Syringic acid 2,3,4-Trimethoxybenzoic acid Ellagic acid 3-Hydroxy-4,5-dimethoxybenzoic acid Reserpine 7,8-DIHYDROXY-6-METHOXYCOUMARIN 3,4,5-Trimethoxyphenylacetic acid 2,3,4-TRIMETHOXYBENZONITRILE 3,4,5-Trimethoxyphenylacetonitrile RESCINNAMINE 3,4,5-TRIMETHOXYCINNAMIC ACID

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