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Methylene Blue

Methylene Blue Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Methylene Blue
CAS:61-73-4
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:61-73-4
CAS:61-73-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Email: info@tnjchem.com
Products Intro: Product Name:Methylene Blue
CAS:61-73-4
Purity:99.9% Package:1KG;5USD
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Methylene Blue
CAS:61-73-4
Purity:99% Package:1kg;1USD
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:methylene blue
CAS:61-73-4
Purity:99% Package:5KG;1KG

Lastest Price from Methylene Blue manufacturers

  • Methylene Blue
  • US $1.00 / kg
  • 2019-07-06
  • CAS:61-73-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: C16H18ClN3S
Methylene Blue Basic information
Product Name:Methylene Blue
Synonyms:METHYLENE BLUE SOLUTION, 0.5% IN WATER;METHYLENE BLUE SOLUTION ALKALINE ACC. TO LOEFFLER;METHYLENE BLUE SOLUTION ACCORDING TO LOE FFLER FOR MICROSCOPY;METHYLENE BLUE CERTIFIED (C.I. 52015) FOR STAINING AND REAGENT FOR SPECTROSCOPY USE;METHYLENE BLUE INDICATOR, HIGH PURITY BIOGICAL STAIN, SPECTROPHOTOMETRIC ANALYSIS & MICROBIOLOGY GRADE 98.5%, C.I.NO 52015;METHYLENE BLUE POLYCHROME;METHYLENE BLUE POLYCHROME (MCFADYEN'S) 1% AQUEOUS STAINING SOLUTION;METHYLENE BLUE TABLETS FOR MILK TESTING
CAS:61-73-4
MF:C16H18ClN3S
MW:319.85
EINECS:200-515-2
Product Categories:Analytical reagent;Indazoles;Analytical Chemistry;Ion Association;Phenothiazine
Mol File:61-73-4.mol
Methylene Blue Structure
Methylene Blue Chemical Properties
Melting point 190 °C (dec.)(lit.)
density 1.0 g/mL at 20 °C
refractive index n20/D1.347
Fp 45 °C
storage temp. Store at RT
solubility Soluble in water, ethanol, ethylene glycol, methyl cellosolve
pka2.6, 11.2(at 25℃)
form Liquid
Colour Index 52015
color Green
Specific Gravity0.98
OdorOdorless
Water Solubility 40 g/L (20 ºC)
λmax661 nm
Merck 14,6060
BRN 3641570
Biological ApplicationsDetecting microorganisms; treating diabetic retinopathy,macular degeneration,malignant uveal melanomas,erysipelas,hidradenitis suppurativa,inflammation,skin diseases
NIST Chemistry ReferenceMethylene blue(61-73-4)
EPA Substance Registry SystemMethylene blue (61-73-4)
Safety Information
Hazard Codes Xn
Risk Statements 10-41-22-20/21/22-36/37/38
Safety Statements 26-39-36
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS SP5740000
HS Code 32049010
Hazardous Substances Data61-73-4(Hazardous Substances Data)
ToxicityLD50 oral in rat: 1180mg/kg
MSDS Information
ProviderLanguage
Methylene Blue English
ACROS English
SigmaAldrich English
ALFA English
Methylene Blue Usage And Synthesis
Chemical Propertiesgreen fine crystalline powder
UsesA useful inhibitor of cGMP-mediated processes and a useful stain
DefinitionChEBI: An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.
HazardToxic by ingestion.
Biological ActivityBiological stain and redox indicator. Inhibits tau filament formation (IC 50 = 1.9 μ M). Also inhibits soluble guanylyl cyclase.
Clinical UseMethylene blue is 3,7-bis(dimethylamino)-phenazathioniumchloride (Urised). The compound occurs as a dark greencrystalline powder with a metallic appearance that is solublein water (1:25) and alcohol (1:65).
Methylene blue has weak antiseptic properties that makeit useful for the treatment of cystitis and urethritis. The actionof methylene blue is considered to be bacteriostatic.The compound colors the urine and stool blue green.
Safety ProfilePoison by ingestion,intraperitoneal, intravenous, and subcutaneous routes.Human systemic effects: cyanosis, blood changes.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits verytoxic fumes of NOx, SOx, and
Veterinary Drugs and TreatmentsMethylene blue is used primarily for treating methemoglobinemia secondary to oxidative agents (nitrates, chlorates) in ruminants. It is also employed occasionally as adjunctive or alternative therapy for cyanide toxicity.
Intra-operative methylene blue is also being used to preferentially stain islet-cell tumors of the pancreas in dogs in order to aid in their surgical removal or in determining the animal’s prognosis.
Purification MethodsCrystallise the chloride from 0.1M 664 2HCl (16mL/g), the crystals are separated by centrifugation, washed with chilled EtOH and diethyl ether, and dried under vacuum. Crystallise it from 50% aqueous EtOH, wash it with absolute EtOH, and dry it at 50-55o for 24hours. It has also been crystallised from *benzene/MeOH (3:1). It has been salted out with NaCl from a commercial concentrated aqueous solution, then crystallised from water, and dried at 100o in an oven for 8-10hours. [Beilstein 27 III/IV 5152.]
Tag:Methylene Blue(61-73-4) Related Product Information
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