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ANTI-PHOSPHO-TAU (PSER199/202)

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ANTI-PHOSPHO-TAU (PSER199/202) Suppliers list
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:Anti-phospho-Tau (pSer199/202)
Purity:affinity isolated antibody, buffered aqueous glycerol soluti Package:1vial Remarks:T6819
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Remarks:affinity isolated antibody, buffered aqueous glycerol solution
Company Name: SIGMA-RBI  
Tel: 800 736 3690 (Orders)
Email:
Products Intro:
ANTI-PHOSPHO-TAU (PSER199/202) Basic information
Product Name:ANTI-PHOSPHO-TAU (PSER199/202)
Synonyms:ANTI-PHOSPHO-TAU (PSER199/202);Anti-phospho-Tau (pSer199/202) antibody produced in rabbit
CAS:
MF:
MW:0
EINECS:
Product Categories:Alphabetical Index;Antibodies for Alzheimer and Neurodegenerative Disease ResearchCell Biology;Antibodies for Neurobiology;Antibodies for Neurodegenerative Diseases Research;Antibodies to Cytoskeleton;Antibodies to Microtubule and Associated ProteinsAntibodies
Mol File:Mol File
ANTI-PHOSPHO-TAU (PSER199/202) Structure
ANTI-PHOSPHO-TAU (PSER199/202) Chemical Properties
storage temp. -20°C
form buffered aqueous glycerol solution
Safety Information
Safety Statements 23-24/25
WGK Germany 1
MSDS Information
ProviderLanguage
SigmaAldrich English
ANTI-PHOSPHO-TAU (PSER199/202) Usage And Synthesis
UsesAnti-phospho-Tau (pSer199/202) antibody (diluted 1:1000 in PBS containing 0.3% Triton X-100 and 0.5% BSA) can be used in immunocytochemistry for identification of protein aggregates. It can also be used as primary antibody (diluted 1: 3000) in immunohistochemistry.
General DescriptionTau proteins are known as microtubule-associated phosphoprotein (MAP) and express mainly in neurons of central nervous system. It has a crucial role in tubulin polymerization and facilitates microtubules assembly and stability. The biological activity of tau proteins depends on degree of its phosphorylation. Anti-phospho-Tau (pSer199/202) antibody can be used in microarray and western blotting. It can also be used in immunoblotting. Rabbit anti- phospho-Tau (pSer199/202) antibody reacts specifically with human Tau (pSer199/202) (45-68 kD).
Biochem/physiol ActionsTau (τ) plays an essential role in the assembly and maintenance of microtubule structure. Deletion of tau (τ) results in developmental delay and learning disability. The gene expression is associated with the development of Alzheimer′s disease (AD). Genetic variation in τ gene increases the risk of susceptibility to the sporadic tauopathies, progressive supranuclear palsy (PSP) and corticobasal degeneration.
ANTI-PHOSPHO-TAU (PSER199/202) Preparation Products And Raw materials
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