- Hypocrellin A
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- $47.00 / 1mg
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2025-12-05
- CAS:77029-83-5
- Min. Order:
- Purity: 99.95%
- Supply Ability: 10g
- Hypocrellin A
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- $0.00 / 5mg
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2023-02-24
- CAS:77029-83-5
- Min. Order: 5mg
- Purity: ≥95%(HPLC)
- Supply Ability: 10 g
- HYPOCRELLIN A
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- $30.00 / 1Kg/Bag
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2020-11-18
- CAS:77029-83-5
- Min. Order: 25Kg/Bag
- Purity: 99%
- Supply Ability: 20 Tons
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| | HYPOCRELLIN A Basic information |
| Product Name: | HYPOCRELLIN A | | Synonyms: | HYPOCRELLIN;HYPOCRELLIN A;1H-Cyclohepta[ghi]perylene-5,12-dione,1-acetyl-2,3-dihydro-2,6,11-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-,stereoisomer;(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione;(11R,12S)-11-acetyl-3,9,12-trihydroxy-1,5,6,10-tetramethoxy-12-methyl-12,13-dihydro-2H-cyclohepta[ghi]perylene-2,8(11H)-dione;(1S,2R)-1-acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-m...;11-epoxide;Dexamethasone 9 | | CAS: | 77029-83-5 | | MF: | C30H26O10 | | MW: | 546.52 | | EINECS: | | | Product Categories: | | | Mol File: | 77029-83-5.mol |  |
| | HYPOCRELLIN A Chemical Properties |
| Melting point | 209-210 °C | | Boiling point | 922.8±65.0 °C(Predicted) | | density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: 2mg/mL; DMSO: 3mg/mL; Ethanol: 0.3mg/mL | | form | A solid | | pka | 7.03±0.60(Predicted) | | color | Brown to red | | InChIKey | URTOHKHBNYPGQJ-UHYDGBJBNA-N | | SMILES | C12C3[C@@H](C(=O)C)[C@](O)(C)CC4=C(C(=O)C5=C(C=C(OC)C(C6C(OC)=CC(=O)C(=C(O)C=3OC)C1=6)=C5C=24)O)OC |&1:2,6,r| |
| | HYPOCRELLIN A Usage And Synthesis |
| Chemical Properties | Red crystal, odorless, tasteless, purity 98%, melting point 209-210 ℃, soluble in chloroform, acetone, ethyl acetate, soluble in methanol, ethanol, slightly soluble in petroleum ether, insoluble in water, not easy to hydrolysis, but in the alkaline environment can be self-sensitive photo-oxidation of photolysis; now the folk used as a drug to treat gastric pain and arthritis and is the treatment of dermatological disorders, anti-tumor, anti-AIDS, the potentially effective It is also a potentially effective photosensitive drug for the treatment of skin diseases, anti-tumor and anti-AIDS. | | Uses | Hypocrellin A is an antimicrobial and antileishmanial activity. Ga(3+)-Hypocrellin interacts with myoglobin in vitro. | | in vivo | Hypocrellin A (2.5 and 5 mg/kg; i.p.; once every two days for fourteen days) inhibits tumor growth in a non-small cell lung cancer xenograft model mouse model[8]. | Animal Model: | H460 cells were inoculated subcutaneously on the backs of BALB/c nude mice[8] | | Dosage: | 2.5 and 5 mg/kg | | Administration: | i.p.; Inject once every two days for fourteen days | | Result: | Induced the expression of the pro-apoptotic protein BAX and inhibited the expression of the anti-apoptotic protein BCL-2 in NSCLC tumors. |
| | IC 50 | Leishmania |
| | HYPOCRELLIN A Preparation Products And Raw materials |
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