Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
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Tel: |
18149758185 |
Email: |
sales-cpd@caerulumpharma.com |
Products Intro: |
Product Name:PF-06928215; PF06928215; PF 06928215; CAS:2378173-15-8 Purity:98% Package:1g;10g;100g
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| PF-06928215 Basic information |
Product Name: | PF-06928215 | Synonyms: | Cyclohexanecarboxylic acid, 2-[[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]amino]-, (1R,2S)-;PF-06928215;Inhibitor,PF-06928215,cGAS,inhibit,PF 06928215,Cyclic GMP-AMP Synthase,PF06928215 | CAS: | 2378173-15-8 | MF: | C20H20N4O4 | MW: | 380.4 | EINECS: | | Product Categories: | | Mol File: | 2378173-15-8.mol | |
| PF-06928215 Chemical Properties |
storage temp. | Store at -20°C | solubility | DMSO: 30 mg/ml | form | A solid |
| PF-06928215 Usage And Synthesis |
Biological Activity | PF-06928215 is a high-affinity cGAS (cyclic GMP-AMP Synthase) inhibitor with IC50 of 4.9 μM and affinity Kd value of 0.2 μM. | in vitro | PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression. |
| PF-06928215 Preparation Products And Raw materials |
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