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Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester

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Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Suppliers list
Company Name: AFINE CHEMICALS LIMITED
Tel: 0571-85134551 18958018566;
Email: info@afinechem.com
Products Intro: Product Name:DOLUTEGRAVIR IMPURITY
CAS:2244161-73-5
Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
Company Name: China National Standard Pharmaceutical Corporation Limited
Tel: +8615391658522
Email: overseasales@yongstandards.com
Products Intro: Product Name:Dolutegravir Impurity 4
CAS:2244161-73-5
Purity:0.95 Package:Vials
Company Name: Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.  
Tel: 020-89854820
Email: sales@jzpharma.cn
Products Intro: Product Name:Dolutegravir Impurity 26
CAS:2244161-73-5
Purity:98% HPLC Package:10MG;25MG;50MG;100MG
Company Name: QUALITY CONTROL SOLUTIONS LTD.  
Tel: 13670046396
Email: ORDERS@QCSRM.COM
Products Intro: Product Name:Dolutegravir Impurity 60
CAS:2244161-73-5
Purity:95% HPLC Package:10MG;25MG;50MG;100MG
Company Name: Shenzhen Roark Pharma-Tec Co., Ltd.  
Tel: 13128912434
Email: 2880126944@qq.com
Products Intro: Product Name:Dolutegravir Impurity 26
CAS:2244161-73-5
Purity:98% HPLC Package:10MG;25MG;50MG;100MG
Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Basic information
Product Name:Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester
Synonyms:DOLUTEGRAVIR IMPURITY;sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-(((2,4-difluorobenzyl)carbamoyl)oxy)butan-2-yl)-1,;Dolutegravir Impurity 60
CAS:2244161-73-5
MF:C28H24F4N4O6
MW:588.51
EINECS:
Product Categories:
Mol File:2244161-73-5.mol
Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Structure
Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Chemical Properties
Boiling point 778.0±60.0 °C(Predicted)
density 1.51±0.1 g/cm3(Predicted)
pka4.50±1.00(Predicted)
Safety Information
MSDS Information
Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Usage And Synthesis
UsesDes-butanoyl 3,4-Didehydro-N-butyl(2,4-difluorobenzyl)carbamate Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Preparation Products And Raw materials
Tag:Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester(2244161-73-5) Related Product Information