| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:SIRT6-IN-2
CAS:891002-11-2
Purity:98% Package:5mg Remarks:S34220
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Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- manufacturers
- SIRT6-IN-5
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- $51.00 / 1mg
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2025-11-09
- CAS:891002-11-2
- Min. Order:
- Purity: 99.23%
- Supply Ability: 10g
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| | Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- Basic information |
| | Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- Chemical Properties |
| Boiling point | 461.6±45.0 °C(Predicted) | | density | 1.520±0.06 g/cm3(Predicted) | | form | Solid | | pka | 2.96±0.10(Predicted) | | color | Off-white to gray |
| | Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- Usage And Synthesis |
| Uses | SIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1]. | | References | [1] Damonte P, et al. SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858. DOI:10.1016/j.bmc.2017.09.023 |
| | Benzoic acid, 5-[[4-[(2-furanylcarbonyl)amino]benzoyl]amino]-2-hydroxy- Preparation Products And Raw materials |
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